C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 22 (organic cation transporter), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146477 SLC22A3 9606 + 6:160348268-160452581 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000275300 SLC22A3-001 160348268-160452581 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000275300
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000275300 2.011±0.00 6.186±0.00 1.022±0.00 0.501±0.01 4.203±0.00 2.407±1.79 0.436±0.00 4.594±2.12 8.763±6.95 2.853±0.52 7.774±5.30 5.196±2.02 10.601±0.92 5.112±3.47

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005329 IEA dopamine transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006855 TAS drug transmembrane transport
GO:0015075 IEA ion transmembrane transporter activity
GO:0015101 IDA organic cation transmembrane transporter activity
GO:0015651 IDA quaternary ammonium group transmembrane transporter activity
GO:0015695 IDA organic cation transport
GO:0015697 IDA quaternary ammonium group transport
GO:0015844 IEA monoamine transport
GO:0015872 IEA dopamine transport
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0019534 IEA toxin transporter activity
GO:0022857 IEA transmembrane transporter activity
GO:0032098 IEA regulation of appetite
GO:0034220 IEA ion transmembrane transport
GO:0044281 TAS small molecule metabolic process
GO:0051608 IEA histamine transport
GO:0051615 IEA histamine uptake
GO:0055085 TAS:IEA transmembrane transport
GO:1901998 IEA toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058775 SLC22A3 solute carrier family 22 (organic cation transporter), member 3 protein_coding Danio_rerio
ENSMUSG00000023828 Slc22a3 solute carrier family 22 (organic cation transporter), member 3 protein_coding Mus_musculus

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