C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146678 IGFBP1 9606 + 7:45888357-45893668 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000275525 IGFBP1-001 45888357-45893668 protein_coding
  ENST00000457280 IGFBP1-002 45888360-45893625 protein_coding
  ENST00000468955 IGFBP1-003 45888497-45893653 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000275525ENST00000457280ENST00000468955
Transcript ID Adrenal Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000275525 N/A 0.189±0.00 0.344±0.00 N/A 0.229±0.00 56.972±0.00 N/A 1.932±1.71 850.506±291.09 0.238±0.00
ENST00000457280 N/A N/A N/A N/A N/A N/A N/A 0.235±0.00 148.640±68.02 N/A
ENST00000468955 0.009±0.00 N/A 0.177±0.00 0.028±0.00 4.965±0.00 N/A 0.201±0.19 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00072L CIL_00072L_0002 CGP 7:45574140-45893668
CIL_0005P5 CIL_0005P5_0002 CGP 7:45888357-45921874

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007165 TAS signal transduction
GO:0008286 IEA insulin receptor signaling pathway
GO:0030307 IEA positive regulation of cell growth
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0042246 IEA tissue regeneration
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014947 igfbp1a insulin-like growth factor binding protein 1a protein_coding Danio_rerio
ENSDARG00000038666 igfbp1b insulin-like growth factor binding protein 1b protein_coding Danio_rerio
ENSMUSG00000020429 Igfbp1 insulin-like growth factor binding protein 1 protein_coding Mus_musculus

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