C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 2 receptor, gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147168 IL2RG 9606 - X:71107404-71112108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276110 IL2RG-006 71107404-71111550 retained_intron
  ENST00000374188 IL2RG-201 71107736-71109268 protein_coding
  ENST00000374202 IL2RG-004 71107404-71111631 protein_coding
  ENST00000456850 IL2RG-202 71107736-71111448 protein_coding
  ENST00000464642 IL2RG-005 71108662-71112108 protein_coding
  ENST00000473378 IL2RG-002 71110597-71111554 protein_coding
  ENST00000482750 IL2RG-003 71107716-71110162 protein_coding
  ENST00000487883 IL2RG-001 71110186-71111560 protein_coding
  ENST00000512747 IL2RG-007 71107409-71111606 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374202ENST00000456850ENST00000464642ENST00000473378ENST00000482750ENST00000512747
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374202 6.859±0.00 86.169±0.00 0.231±0.00 0.212±0.16 2.949±0.21 1.387±0.99 0.331±0.21 1.610±0.00 0.245±0.00 7.787±4.69 N/A 8.351±4.89 11.066±3.49 0.901±0.04
ENST00000456850 N/A N/A N/A N/A N/A 1.091±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000464642 N/A N/A N/A N/A 3.094±0.00 N/A N/A 0.654±0.58 0.490±0.00 2.020±0.00 0.543±0.00 3.003±0.00 N/A N/A
ENST00000473378 N/A N/A 1.321±0.00 0.305±0.00 N/A N/A N/A N/A 1.240±0.00 N/A N/A N/A N/A N/A
ENST00000482750 N/A N/A N/A N/A N/A N/A N/A 3.332±0.00 1.010±0.00 N/A N/A N/A N/A N/A
ENST00000512747 N/A N/A N/A N/A N/A 0.585±0.00 0.034±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YK CIL_0000YK_0002 CGP X:71103889-71112108
CIL_00057U CIL_00057U_0001 CGP X:71107404-71142454

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004896 IEA cytokine receptor activity
GO:0004911 TAS interleukin-2 receptor activity
GO:0004913 TAS interleukin-4 receptor activity
GO:0004917 TAS interleukin-7 receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007165 NAS signal transduction
GO:0009897 ISS external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016020 IEA:IDA membrane
GO:0016032 IEA viral process
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019976 ISS interleukin-2 binding
GO:0019982 IEA interleukin-7 binding
GO:0035771 TAS interleukin-4-mediated signaling pathway
GO:0038110 TAS interleukin-2-mediated signaling pathway
GO:0038111 TAS interleukin-7-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053702 il2rgb interleukin 2 receptor, gamma b protein_coding Danio_rerio
ENSDARG00000068858 il2rga interleukin 2 receptor, gamma a protein_coding Danio_rerio
ENSMUSG00000031304 Il2rg interleukin 2 receptor, gamma chain protein_coding Mus_musculus
ENSMUSG00000092463 Gm20489 predicted gene 20489 protein_coding Mus_musculus

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