C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoribosyl pyrophosphate synthetase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147224 PRPS1 9606 + X:107628424-107651026 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372418 PRPS1-003 107639358-107650301 protein_coding
  ENST00000372419 PRPS1-002 107628530-107641124 protein_coding
  ENST00000372428 PRPS1-201 107628424-107651026 protein_coding
  ENST00000372435 PRPS1-001 107628507-107651026 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372418ENST00000372419ENST00000372435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372418 N/A N/A N/A N/A N/A 1.012±0.00 1.652±0.78 N/A 3.447±0.00 6.938±0.00 3.510±0.60 N/A 2.284±0.00 4.599±0.00
ENST00000372419 5.602±0.00 N/A N/A N/A 3.376±0.00 N/A 0.686±0.00 N/A N/A 2.515±0.00 2.089±0.00 N/A N/A N/A
ENST00000372435 9.560±0.00 15.181±0.00 1.203±0.00 12.856±5.34 5.934±2.81 5.640±4.70 3.134±2.48 9.059±1.11 6.796±5.73 9.944±6.08 6.639±3.65 13.553±5.12 8.132±1.43 8.929±0.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JF CIL_0006JF_0001 CGP X:107522450-107651026
CIL_0006JE CIL_0006JE_0001 CGP X:107628424-107777342

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004749 IEA ribose phosphate diphosphokinase activity
GO:0005524 IDA ATP binding
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006015 IEA 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006144 IMP purine nucleobase metabolic process
GO:0006164 IMP purine nucleotide biosynthetic process
GO:0006221 NAS pyrimidine nucleotide biosynthetic process
GO:0007399 IMP nervous system development
GO:0008219 IEA cell death
GO:0009116 IEA nucleoside metabolic process
GO:0009156 IEA ribonucleoside monophosphate biosynthetic process
GO:0009165 IEA nucleotide biosynthetic process
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0034418 IMP urate biosynthetic process
GO:0042803 IPI protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046101 IMP hypoxanthine biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037506 prps1b phosphoribosyl pyrophosphate synthetase 1B protein_coding Danio_rerio
ENSMUSG00000031432 Prps1 phosphoribosyl pyrophosphate synthetase 1 protein_coding Mus_musculus
ENSMUSG00000079104 Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 protein_coding Mus_musculus

Loading