C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: docking protein 2, 56kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147443 DOK2 9606 - 8:21908873-21913860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276420 DOK2-001 21908873-21913860 protein_coding
  ENST00000517422 DOK2-002 21909615-21913690 nonsense_mediated_decay
  ENST00000518197 DOK2-007 21909635-21913663 protein_coding
  ENST00000522011 DOK2-003 21909834-21911075 retained_intron
  ENST00000523932 DOK2-004 21909829-21913676 protein_coding
  ENST00000524001 DOK2-005 21909464-21912567 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276420ENST00000517422ENST00000518197ENST00000522011ENST00000523932ENST00000524001
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276420 N/A N/A 0.192±0.00 0.064±0.04 0.260±0.00 N/A 0.055±0.00 N/A 0.216±0.00 0.419±0.00 0.114±0.00 0.827±0.80 3.045±0.00 N/A
ENST00000517422 2.968±0.00 6.327±0.00 N/A N/A 3.464±0.00 0.624±0.00 1.232±0.00 N/A 0.945±0.00 4.677±2.58 N/A 1.302±0.02 7.659±0.70 1.296±0.00
ENST00000518197 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.195±0.00 0.476±0.00 N/A N/A
ENST00000522011 N/A N/A N/A N/A 1.427±0.00 N/A N/A N/A N/A N/A N/A 1.552±0.00 N/A N/A
ENST00000523932 N/A 7.621±0.00 N/A 0.303±0.00 N/A 0.203±0.00 0.322±0.00 0.917±0.00 0.915±0.00 N/A 0.132±0.00 N/A 4.144±0.00 N/A
ENST00000524001 N/A N/A N/A N/A N/A N/A N/A N/A 0.202±0.00 1.353±0.00 N/A 0.827±0.00 9.369±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000810 CIL_000810_0001 VISTA 8:21687877-22288944
CIL_0005VE CIL_0005VE_0003 CGP 8:21690403-21913860
CIL_0008ZI CIL_0008ZI_0001 VISTA 8:21743578-22344815
CIL_000812 CIL_000812_0001 VISTA 8:21749915-22350771
CIL_0005W4 CIL_0005W4_0002 CGP 8:21908873-22006585

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005068 IEA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005158 IEA insulin receptor binding
GO:0005829 TAS cytosol
GO:0007165 TAS signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007265 IEA Ras protein signal transduction
GO:0007596 TAS blood coagulation
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075818 dok2 docking protein 2 protein_coding Danio_rerio
ENSDARG00000087271 DOK2 (2 of 2) docking protein 2, 56kDa protein_coding Danio_rerio
ENSMUSG00000022102 Dok2 docking protein 2 protein_coding Mus_musculus

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