C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147459 DOCK5 9606 + 8:25184723-25418082 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276440 DOCK5-001 25184865-25415716 protein_coding
  ENST00000410074 DOCK5-002 25184723-25271221 protein_coding
  ENST00000444569 DOCK5-004 25298942-25376859 protein_coding
  ENST00000463457 DOCK5-011 25391889-25395822 retained_intron
  ENST00000467709 DOCK5-015 25325426-25412256 nonsense_mediated_decay
  ENST00000478099 DOCK5-006 25308739-25310507 retained_intron
  ENST00000479547 DOCK5-012 25409997-25418082 retained_intron
  ENST00000481100 DOCK5-003 25184772-25305307 protein_coding
  ENST00000481728 DOCK5-008 25351393-25364777 retained_intron
  ENST00000487948 DOCK5-007 25310468-25317370 retained_intron
  ENST00000495236 DOCK5-005 25296582-25299470 retained_intron
  ENST00000521405 DOCK5-014 25409432-25412258 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276440ENST00000467709
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276440 0.884±0.00 1.034±0.00 0.947±0.00 3.651±1.29 1.370±0.98 4.389±0.00 2.047±0.41 1.940±0.30 0.743±0.25 2.167±1.30 0.278±0.00 2.162±0.88 4.098±2.47 2.507±0.00
ENST00000467709 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.770±0.00 0.131±0.00 N/A N/A 1.444±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0007264 IEA small GTPase mediated signal transduction
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001968 dock5 dedicator of cytokinesis 5 protein_coding Danio_rerio
ENSMUSG00000044447 Dock5 dedicator of cytokinesis 5 protein_coding Mus_musculus

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