C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cerberus 1, DAN family BMP antagonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147869 CER1 9606 - 9:14719724-14722717 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380911 CER1-001 14719724-14722717 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartTestisENST00000380911
Transcript ID Adrenal Brain Breast Heart Testis
ENST00000380911 0.062±0.00 0.013±0.00 0.175±0.00 0.023±0.00 0.054±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000943 CIL_000943_0001 VISTA 9:14449160-15052146
CIL_000144 CIL_000144_0001 CGP 9:14611071-14722717
CIL_000149 CIL_000149_0001 CGP 9:14719724-14910995

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001657 ISS ureteric bud development
GO:0003419 ISS growth plate cartilage chondrocyte proliferation
GO:0005125 IEA cytokine activity
GO:0005576 ISS extracellular region
GO:0005615 ISS extracellular space
GO:0007369 ISS gastrulation
GO:0007399 IMP nervous system development
GO:0008285 ISS negative regulation of cell proliferation
GO:0009948 ISS anterior/posterior axis specification
GO:0009952 ISS anterior/posterior pattern specification
GO:0016015 IDA morphogen activity
GO:0023019 ISS signal transduction involved in regulation of gene expression
GO:0030282 IMP bone mineralization
GO:0030509 TAS BMP signaling pathway
GO:0030514 ISS negative regulation of BMP signaling pathway
GO:0032926 ISS negative regulation of activin receptor signaling pathway
GO:0035582 ISS sequestering of BMP in extracellular matrix
GO:0036122 IDA BMP binding
GO:0042074 ISS cell migration involved in gastrulation
GO:0042803 ISS protein homodimerization activity
GO:0048263 IMP determination of dorsal identity
GO:0071773 ISS cellular response to BMP stimulus
GO:2000381 ISS negative regulation of mesoderm development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036471 dand5 DAN domain family, member 5 protein_coding Danio_rerio
ENSMUSG00000038192 Cer1 cerberus 1 homolog (Xenopus laevis) protein_coding Mus_musculus

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