C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E synthase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148334 PTGES2 9606 - 9:128120693-128128462 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277462 PTGES2-201 128120694-128128462 protein_coding
  ENST00000338961 PTGES2-001 128120693-128128462 protein_coding
  ENST00000449878 PTGES2-007 128122466-128127724 protein_coding
  ENST00000474124 PTGES2-010 128122448-128127675 processed_transcript
  ENST00000476655 PTGES2-012 128120751-128123755 retained_intron
  ENST00000476748 PTGES2-004 128122991-128128395 processed_transcript
  ENST00000483625 PTGES2-009 128123008-128127709 processed_transcript
  ENST00000485237 PTGES2-006 128125244-128128114 processed_transcript
  ENST00000485510 PTGES2-008 128124331-128127711 retained_intron
  ENST00000487063 PTGES2-005 128122446-128128146 processed_transcript
  ENST00000493205 PTGES2-011 128120752-128125253 retained_intron
  ENST00000496594 PTGES2-014 128120723-128127717 retained_intron
  ENST00000497109 PTGES2-003 128123122-128128418 processed_transcript
  ENST00000617202 PTGES2-202 128120694-128128188 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000277462ENST00000338961ENST00000449878ENST00000474124ENST00000476655ENST00000483625ENST00000493205ENST00000496594ENST00000497109ENST00000617202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000277462 N/A N/A N/A N/A N/A 2.263±0.00 N/A N/A 1.428±0.00 N/A N/A N/A 2.652±0.00 N/A
ENST00000338961 N/A N/A N/A 2.728±0.00 1.714±0.00 4.022±0.00 0.877±0.00 2.318±0.00 N/A N/A 4.235±0.00 8.766±2.46 3.539±0.00 1.508±0.00
ENST00000449878 3.939±0.00 N/A N/A N/A N/A N/A 14.231±0.00 N/A N/A 6.392±0.00 20.028±0.00 10.890±0.00 N/A N/A
ENST00000474124 N/A N/A N/A N/A N/A 4.193±0.00 9.319±0.00 N/A 4.811±0.00 N/A N/A 10.445±0.00 6.693±0.00 4.727±0.00
ENST00000476655 7.365±0.00 10.951±0.00 N/A 14.285±0.00 11.968±5.23 6.717±0.00 7.628±0.00 12.586±0.00 7.555±0.00 N/A N/A 4.828±0.00 N/A 13.387±0.00
ENST00000483625 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.742±0.00 N/A N/A N/A N/A
ENST00000493205 N/A 13.467±0.00 1.517±0.00 5.128±0.00 N/A N/A N/A N/A 1.324±0.00 2.242±0.80 N/A 10.493±1.62 4.344±0.00 3.759±0.00
ENST00000496594 N/A N/A N/A N/A N/A N/A 0.880±0.00 5.734±0.00 N/A N/A N/A 5.164±0.00 3.635±0.00 N/A
ENST00000497109 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.669±0.00
ENST00000617202 N/A 8.167±0.00 N/A 7.882±0.00 N/A N/A N/A 5.054±3.00 N/A 4.334±0.00 8.677±0.00 18.434±7.37 3.161±0.00 1.573±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IEA prostaglandin biosynthetic process
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0009055 IEA electron carrier activity
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0016021 IEA integral component of membrane
GO:0016829 ISS lyase activity
GO:0020037 ISS heme binding
GO:0043295 ISS glutathione binding
GO:0045454 IEA cell redox homeostasis
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046903 IEA secretion
GO:0050220 IEA prostaglandin-E synthase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068415 ptgesl prostaglandin E synthase 2-like protein_coding Danio_rerio
ENSMUSG00000026820 Ptges2 prostaglandin E synthase 2 protein_coding Mus_musculus

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