C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane channel-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149488 TMC2 9606 + 20:2536607-2641784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358864 TMC2-001 2536607-2641784 protein_coding
  ENST00000496948 TMC2-002 2602166-2618379 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000358864ENST00000496948
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000358864 0.208±0.00 0.040±0.00 0.011±0.00 0.089±0.00 0.157±0.00 0.016±0.00 N/A 0.029±0.02 0.494±0.00 0.054±0.00 0.026±0.00 0.130±0.08
ENST00000496948 0.063±0.00 0.122±0.00 N/A 0.161±0.00 0.079±0.00 0.061±0.00 0.085±0.00 0.004±0.00 0.084±0.00 0.017±0.00 0.018±0.00 0.160±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SG CIL_0007SG_0001 VISTA 20:2438562-3039143
CIL_0000FW CIL_0000FW_0001 CGP 20:2536607-2658393

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IEA voltage-gated calcium channel activity
GO:0016021 IEA integral component of membrane
GO:0032426 IEA stereocilium bundle tip
GO:0050910 IEA detection of mechanical stimulus involved in sensory perception of sound
GO:0060005 IEA vestibular reflex
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030311 TMC2 (1 of 2) transmembrane channel-like 2 protein_coding Danio_rerio
ENSDARG00000033104 TMC2 (2 of 2) transmembrane channel-like 2 protein_coding Danio_rerio
ENSMUSG00000060332 Tmc2 transmembrane channel-like gene family 2 protein_coding Mus_musculus

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