C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, beta 3 (phosphatidylinositol-specific)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149782 PLCB3 9606 + 11:64251523-64269150 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000279230 PLCB3-001 64251523-64267921 protein_coding
  ENST00000325234 PLCB3-004 64251575-64267923 protein_coding
  ENST00000536243 PLCB3-003 64263380-64265006 retained_intron
  ENST00000540288 PLCB3-002 64251547-64269150 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000279230ENST00000325234ENST00000540288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000279230 4.093±0.00 0.689±0.00 0.234±0.00 0.230±0.12 1.662±1.23 2.542±1.23 1.059±0.44 6.232±0.00 0.850±0.04 3.614±1.83 3.156±0.00 7.543±5.86 7.256±1.00 5.428±0.49
ENST00000325234 4.835±0.00 3.036±0.00 0.093±0.00 1.324±0.00 3.539±0.00 4.137±0.00 1.212±0.00 1.922±0.00 1.060±0.00 3.765±0.00 N/A 7.001±3.35 N/A 4.854±3.57
ENST00000540288 N/A N/A N/A 0.193±0.00 1.330±0.32 N/A 0.310±0.00 N/A N/A 0.710±0.00 0.639±0.00 2.457±1.22 1.761±0.46 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003073 IDA regulation of systemic arterial blood pressure
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004629 TAS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005516 IPI calmodulin binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006629 IEA lipid metabolic process
GO:0007165 IEA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0016020 IEA membrane
GO:0016042 IEA lipid catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0043234 IDA protein complex
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068246 plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) protein_coding Danio_rerio
ENSMUSG00000024960 Plcb3 phospholipase C, beta 3 protein_coding Mus_musculus

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