C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TAO kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149930 TAOK2 9606 + 16:29973641-29992261 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000279394 TAOK2-001 29974281-29992261 protein_coding
  ENST00000308893 TAOK2-002 29973641-29988398 protein_coding
  ENST00000416441 TAOK2-004 29980352-29988398 protein_coding
  ENST00000543033 TAOK2-003 29974182-29988181 protein_coding
  ENST00000566552 TAOK2-005 29985118-29987971 retained_intron
  ENST00000570844 TAOK2-007 29989910-29991710 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000279394ENST00000308893ENST00000416441ENST00000543033ENST00000566552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000279394 18.625±0.00 15.316±0.00 0.803±0.00 7.739±6.04 12.615±0.00 4.122±3.21 3.984±0.00 7.706±0.00 3.361±0.00 14.313±0.00 2.001±0.28 9.215±5.29 7.705±2.93 8.668±2.37
ENST00000308893 11.726±0.00 10.592±0.00 N/A 4.140±1.64 4.315±2.44 3.730±2.00 4.538±2.33 4.007±1.74 2.860±0.67 5.720±3.35 1.456±0.47 6.403±4.98 7.309±3.79 7.188±4.72
ENST00000416441 N/A N/A N/A N/A N/A 0.441±0.00 N/A N/A N/A N/A 0.494±0.00 N/A N/A N/A
ENST00000543033 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.021±0.00
ENST00000566552 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.701±0.00 10.183±0.00 15.504±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0001558 NAS regulation of cell growth
GO:0003677 IEA DNA binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006468 IEA protein phosphorylation
GO:0006612 NAS protein targeting to membrane
GO:0006915 NAS apoptotic process
GO:0006950 IDA response to stress
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008360 IDA regulation of cell shape
GO:0016021 IEA integral component of membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016477 NAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030036 IDA actin cytoskeleton organization
GO:0031434 IPI mitogen-activated protein kinase kinase binding
GO:0031572 IMP G2 DNA damage checkpoint
GO:0032874 IMP positive regulation of stress-activated MAPK cascade
GO:0042995 IEA cell projection
GO:0043235 IDA receptor complex
GO:0046330 IDA positive regulation of JNK cascade
GO:0048041 IDA focal adhesion assembly
GO:0051403 IDA stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074899 taok2a TAO kinase 2a protein_coding Danio_rerio
ENSDARG00000079261 taok2b TAO kinase 2b protein_coding Danio_rerio
ENSDARG00000096611 taok2b TAO kinase 2b protein_coding Danio_rerio
ENSMUSG00000059981 Taok2 TAO kinase 2 protein_coding Mus_musculus

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