C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fli-1 proto-oncogene, ETS transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151702 FLI1 9606 + 11:128686535-128813267 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000281428 FLI1-201 128693916-128813266 protein_coding
  ENST00000344954 FLI1-202 128686535-128813266 protein_coding
  ENST00000429175 FLI1-002 128694088-128812417 nonsense_mediated_decay
  ENST00000527767 FLI1-008 128692982-128772813 protein_coding
  ENST00000527786 FLI1-001 128693770-128813267 protein_coding
  ENST00000528790 FLI1-006 128803876-128812416 retained_intron
  ENST00000534087 FLI1-003 128694092-128813267 protein_coding
  ENST00000608055 FLI1-007 128758106-128768516 retained_intron
  ENST00000608303 FLI1-004 128686535-128812416 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000429175ENST00000527786ENST00000528790ENST00000534087ENST00000608303
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000429175 19.908±0.00 22.230±0.00 0.840±0.00 1.126±0.96 4.754±3.92 4.825±4.27 3.380±1.57 2.655±1.61 2.014±0.34 8.993±4.84 1.847±1.63 2.288±1.35 12.838±5.43 3.307±3.03
ENST00000527786 N/A N/A 0.338±0.00 N/A 1.051±0.00 N/A N/A N/A 0.467±0.00 N/A N/A 0.962±0.00 N/A N/A
ENST00000528790 N/A N/A 0.245±0.00 0.040±0.00 0.714±0.00 N/A N/A N/A 0.274±0.00 2.037±0.00 0.276±0.00 0.354±0.19 N/A 0.258±0.00
ENST00000534087 N/A N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A 2.278±0.00 N/A N/A N/A N/A
ENST00000608303 N/A N/A N/A 0.449±0.00 N/A 1.189±0.00 N/A N/A N/A N/A 0.236±0.00 1.984±0.65 8.155±0.00 1.225±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050X CIL_00050X_0002 CGP 11:128458761-128813267
CIL_00050W CIL_00050W_0002 CGP 11:128686535-128867373

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 TAS DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IBA:IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0007599 TAS hemostasis
GO:0008015 IEA blood circulation
GO:0009887 IEA organ morphogenesis
GO:0030154 IBA cell differentiation
GO:0035855 IEA megakaryocyte development
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054632 fli1a friend leukemia integration 1a protein_coding Danio_rerio
ENSMUSG00000016087 Fli1 Friend leukemia integration 1 protein_coding Mus_musculus

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