C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PAN3 poly(A) specific ribonuclease subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152520 PAN3 9606 + 13:28138506-28295335 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380958 PAN3-002 28138506-28292539 protein_coding
  ENST00000399613 PAN3-001 28139033-28295335 protein_coding
  ENST00000483842 PAN3-003 28239557-28256539 processed_transcript
  ENST00000503791 PAN3-004 28138506-28272313 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380958ENST00000399613
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380958 N/A N/A 1.122±0.00 N/A N/A 3.017±0.00 N/A N/A 6.417±0.00 3.295±0.00 0.541±0.00 N/A N/A N/A
ENST00000399613 3.861±0.00 3.183±0.00 1.722±0.00 0.401±0.00 2.110±0.35 2.705±0.89 0.807±0.55 2.556±0.00 0.396±0.00 1.144±0.47 1.029±0.71 6.211±4.38 1.321±0.79 8.589±1.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MT CIL_0007MT_0001 UCNEbase 13:27505095-28294517
CIL_0000G0 CIL_0000G0_0002 CGP 13:28003274-28295335
CIL_0000G1 CIL_0000G1_0002 CGP 13:28138506-28495128

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 IEA deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 IEA cytoplasmic mRNA processing body
GO:0004535 IDA poly(A)-specific ribonuclease activity
GO:0004672 IEA protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006605 IEA protein targeting
GO:0010467 TAS gene expression
GO:0010606 IEA positive regulation of cytoplasmic mRNA processing body assembly
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031251 IDA PAN complex
GO:0046872 IEA metal ion binding
GO:0090503 IDA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031637 pan3 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000029647 Pan3 PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae) protein_coding Mus_musculus

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