C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152767 FARP1 9606 + 13:98142562-98455176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319562 FARP1-001 98143251-98455176 protein_coding
  ENST00000376581 FARP1-006 98143480-98245304 protein_coding
  ENST00000423063 FARP1-005 98431043-98436101 protein_coding
  ENST00000427404 FARP1-009 98328718-98333238 processed_transcript
  ENST00000457029 FARP1-003 98404071-98425498 processed_transcript
  ENST00000457431 FARP1-008 98328880-98333238 processed_transcript
  ENST00000490389 FARP1-002 98384361-98385786 retained_intron
  ENST00000593548 FARP1-042 98383606-98385766 processed_transcript
  ENST00000593990 FARP1-036 98328783-98333161 processed_transcript
  ENST00000594346 FARP1-019 98445153-98447844 retained_intron
  ENST00000594657 FARP1-037 98328785-98333768 processed_transcript
  ENST00000595366 FARP1-029 98328778-98333238 processed_transcript
  ENST00000595380 FARP1-033 98328778-98388478 processed_transcript
  ENST00000595437 FARP1-011 98142562-98449773 protein_coding
  ENST00000595817 FARP1-040 98328228-98384831 processed_transcript
  ENST00000596256 FARP1-013 98431081-98440796 protein_coding
  ENST00000596467 FARP1-034 98328778-98385995 retained_intron
  ENST00000596545 FARP1-031 98328778-98334349 processed_transcript
  ENST00000596580 FARP1-017 98399286-98407494 retained_intron
  ENST00000596613 FARP1-027 98328778-98377918 processed_transcript
  ENST00000597596 FARP1-014 98449011-98449770 processed_transcript
  ENST00000597777 FARP1-018 98431157-98434997 retained_intron
  ENST00000598346 FARP1-026 98328778-98338879 processed_transcript
  ENST00000598389 FARP1-039 98177817-98384844 protein_coding
  ENST00000598698 FARP1-023 98328778-98332871 processed_transcript
  ENST00000599040 FARP1-016 98331758-98385754 protein_coding
  ENST00000599151 FARP1-022 98328778-98332880 processed_transcript
  ENST00000600032 FARP1-028 98328778-98384832 processed_transcript
  ENST00000600190 FARP1-012 98390585-98395420 retained_intron
  ENST00000600380 FARP1-015 98448874-98449515 processed_transcript
  ENST00000600648 FARP1-010 98143180-98213232 processed_transcript
  ENST00000601009 FARP1-038 98377821-98389693 protein_coding
  ENST00000601133 FARP1-035 98328780-98345610 processed_transcript
  ENST00000601361 FARP1-007 98328191-98343812 processed_transcript
  ENST00000601656 FARP1-020 98328778-98329754 processed_transcript
  ENST00000601762 FARP1-030 98328778-98333235 processed_transcript
  ENST00000601853 FARP1-032 98328778-98382540 processed_transcript
  ENST00000602015 FARP1-021 98328778-98329984 processed_transcript
  ENST00000602171 FARP1-025 98328778-98338879 processed_transcript
  ENST00000602263 FARP1-041 98340689-98385766 processed_transcript
  ENST00000602272 FARP1-024 98328778-98338758 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000319562ENST00000595437ENST00000596580
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000319562 N/A N/A N/A N/A N/A N/A N/A 1.486±0.00 N/A N/A N/A
ENST00000595437 7.849±0.00 12.717±0.00 3.959±0.00 4.997±0.00 N/A 7.837±5.03 N/A N/A 8.725±1.58 9.807±1.13 10.375±0.53
ENST00000596580 N/A 12.657±0.00 4.869±0.17 3.356±0.00 3.224±0.00 2.844±0.92 4.242±0.00 2.562±0.00 4.520±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004FZ CIL_0004FZ_0002 CGP 13:97953658-98455176

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 TAS:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005856 IEA cytoskeleton
GO:0007416 ISS synapse assembly
GO:0008092 IEA cytoskeletal protein binding
GO:0010923 IDA negative regulation of phosphatase activity
GO:0030054 IEA cell junction
GO:0030425 ISS dendrite
GO:0030676 ISS Rac guanyl-nucleotide exchange factor activity
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0045202 IEA synapse
GO:0048365 IEA Rac GTPase binding
GO:0048813 ISS dendrite morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063695 FARP1 (1 of 2) FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) protein_coding Danio_rerio
ENSDARG00000074381 farp1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) protein_coding Danio_rerio
ENSMUSG00000025555 Farp1 FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) protein_coding Mus_musculus

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