C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GRB2-related adaptor protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154016 GRAP 9606 - 17:19020673-19047637 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284154 GRAP-001 19020673-19047637 protein_coding
  ENST00000395635 GRAP-002 19021863-19042485 protein_coding
  ENST00000571380 GRAP-004 19035732-19047011 retained_intron
  ENST00000573099 GRAP-003 19021669-19046997 protein_coding
  ENST00000583020 GRAP-006 19021939-19046960 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverLungENST00000284154ENST00000395635
Transcript ID Brain Heart Kidney Liver Lung
ENST00000284154 0.097±0.00 0.090±0.00 N/A 0.178±0.00 N/A
ENST00000395635 N/A N/A 2.402±0.00 N/A 1.415±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000180 CIL_000180_0002 CGP 17:18950345-19022595
CIL_00017V CIL_00017V_0003 CGP 17:18968789-19047637

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IEA protein binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0007265 TAS Ras protein signal transduction
GO:0007267 TAS cell-cell signaling
GO:0009967 TAS positive regulation of signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005414 grapa GRB2-related adaptor protein a protein_coding Danio_rerio
ENSDARG00000022668 grapb GRB2-related adaptor protein b protein_coding Danio_rerio
ENSMUSG00000004837 Grap GRB2-related adaptor protein protein_coding Mus_musculus

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