C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GA binding protein transcription factor, alpha subunit 60kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154727 GABPA 9606 + 21:25734570-25772460 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354828 GABPA-002 25734570-25772460 protein_coding
  ENST00000400075 GABPA-001 25735384-25772460 protein_coding
  ENST00000487266 GABPA-003 25735389-25752348 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354828ENST00000400075
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354828 N/A N/A 3.266±0.00 3.045±0.00 N/A 1.473±0.00 N/A N/A N/A N/A 1.797±0.00 N/A 3.807±0.06
ENST00000400075 5.530±0.00 4.530±0.00 2.348±0.00 2.808±0.54 2.723±0.00 N/A 5.487±0.00 3.861±1.13 5.966±2.14 2.436±1.02 4.481±0.70 5.997±0.00 6.685±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ML CIL_0000ML_0002 CGP 21:25639272-25735673
CIL_0000RF CIL_0000RF_0001 CGP 21:25716503-25772460
CIL_0000MM CIL_0000MM_0002 CGP 21:25734570-26171128

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IEA in utero embryonic development
GO:0003677 TAS DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0030154 IBA cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045653 IEA negative regulation of megakaryocyte differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069289 gabpa GA-binding protein transcription factor, alpha subunit protein_coding Danio_rerio
ENSMUSG00000008976 Gabpa GA repeat binding protein, alpha protein_coding Mus_musculus

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