C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TSEN2 tRNA splicing endonuclease subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154743 TSEN2 9606 + 3:12484432-12539623 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284995 TSEN2-001 12484511-12533317 protein_coding
  ENST00000402228 TSEN2-002 12484491-12533317 protein_coding
  ENST00000412698 TSEN2-008 12529871-12539620 protein_coding
  ENST00000415684 TSEN2-006 12489780-12533659 protein_coding
  ENST00000444864 TSEN2-201 12484511-12531013 protein_coding
  ENST00000446004 TSEN2-004 12484432-12528924 protein_coding
  ENST00000454502 TSEN2-003 12484443-12533317 protein_coding
  ENST00000455118 TSEN2-007 12529779-12539288 nonsense_mediated_decay
  ENST00000473755 TSEN2-005 12484511-12539623 retained_intron
  ENST00000475595 TSEN2-009 12530848-12533307 processed_transcript
  ENST00000490981 TSEN2-010 12503446-12505574 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284995ENST00000402228ENST00000412698ENST00000415684ENST00000444864ENST00000446004ENST00000454502ENST00000455118ENST00000473755ENST00000475595
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284995 N/A N/A N/A N/A 0.659±0.00 N/A N/A N/A 1.091±0.57 N/A 1.068±0.00 1.137±0.00 0.472±0.00 1.365±0.57
ENST00000402228 0.774±0.00 N/A 0.295±0.00 0.817±0.24 N/A N/A 0.352±0.00 0.800±0.00 N/A N/A N/A 2.208±0.57 N/A N/A
ENST00000412698 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.509±0.00 2.555±1.16 N/A N/A N/A
ENST00000415684 N/A 1.252±0.00 N/A 0.610±0.00 0.823±0.00 1.500±0.00 N/A 0.731±0.43 N/A 0.245±0.13 N/A 1.350±0.10 0.733±0.04 0.942±0.00
ENST00000444864 N/A N/A 0.483±0.00 N/A N/A 0.731±0.00 0.387±0.00 N/A N/A N/A N/A 2.304±0.54 N/A 0.855±0.00
ENST00000446004 N/A N/A N/A N/A 1.696±0.00 1.800±0.00 1.635±0.00 N/A N/A 0.758±0.00 1.730±0.14 3.414±0.00 1.060±0.00 2.481±0.53
ENST00000454502 N/A N/A N/A 0.555±0.00 N/A N/A N/A N/A N/A N/A N/A 2.737±1.23 N/A N/A
ENST00000455118 N/A 2.746±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.744±0.00 N/A N/A N/A
ENST00000473755 N/A N/A N/A N/A N/A N/A N/A N/A 0.473±0.32 0.640±0.00 N/A 1.968±0.00 N/A N/A
ENST00000475595 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.422±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004K9 CIL_0004K9_0001 CGP 3:12287368-12539623
CIL_0005SH CIL_0005SH_0001 CGP 3:12484432-12561059

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000213 IEA tRNA-intron endonuclease activity
GO:0000214 IEA tRNA-intron endonuclease complex
GO:0003676 IEA nucleic acid binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006388 IEA:IDA tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006397 IEA mRNA processing
GO:0016829 IEA lyase activity
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091851 tsen2 tRNA splicing endonuclease 2 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000042389 Tsen2 tRNA splicing endonuclease 2 homolog (S. cerevisiae) protein_coding Mus_musculus

Loading