C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154928 EPHB1 9606 + 3:134597801-135260467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000398015 EPHB1-005 134795262-135260467 protein_coding
  ENST00000460895 EPHB1-004 134615365-134951651 protein_coding
  ENST00000467013 EPHB1-002 134597801-134601119 processed_transcript
  ENST00000467708 EPHB1-003 134597879-134779899 processed_transcript
  ENST00000472904 EPHB1-001 134597824-134628104 processed_transcript
  ENST00000473867 EPHB1-013 134823848-134951621 protein_coding
  ENST00000474732 EPHB1-011 134852506-134951762 protein_coding
  ENST00000482618 EPHB1-007 134795262-135132766 nonsense_mediated_decay
  ENST00000488154 EPHB1-009 134795632-135132815 processed_transcript
  ENST00000488992 EPHB1-014 135132792-135154402 retained_intron
  ENST00000493838 EPHB1-006 135067532-135259370 protein_coding
  ENST00000497173 EPHB1-012 134796141-134951441 protein_coding
  ENST00000617754 EPHB1-201 134795632-135259127 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000398015ENST00000460895ENST00000467708ENST00000472904ENST00000474732ENST00000482618ENST00000488154ENST00000493838ENST00000617754
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000398015 0.087±0.00 0.544±0.00 N/A 3.279±1.96 0.734±0.69 N/A 0.717±0.00 0.051±0.02 4.930±0.00 0.703±0.49 0.016±0.00 1.349±0.46
ENST00000460895 N/A N/A N/A N/A N/A N/A N/A 0.588±0.00 N/A N/A N/A N/A
ENST00000467708 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.076±0.03 N/A
ENST00000472904 N/A N/A N/A N/A N/A N/A N/A 1.029±0.42 N/A N/A N/A N/A
ENST00000474732 N/A N/A N/A N/A N/A N/A N/A 0.318±0.00 N/A N/A N/A N/A
ENST00000482618 N/A N/A N/A N/A N/A N/A 0.698±0.00 N/A N/A N/A N/A N/A
ENST00000488154 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.041±0.00 N/A
ENST00000493838 N/A N/A 0.253±0.00 N/A N/A 0.153±0.00 N/A N/A N/A 0.858±0.54 N/A 1.825±0.00
ENST00000617754 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.481±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005005 IDA transmembrane-ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 ISS axon guidance
GO:0008046 IEA axon guidance receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021545 IEA cranial nerve development
GO:0021631 IEA optic nerve morphogenesis
GO:0021952 ISS central nervous system projection neuron axonogenesis
GO:0022008 ISS neurogenesis
GO:0030010 ISS establishment of cell polarity
GO:0030424 IEA axon
GO:0031290 ISS retinal ganglion cell axon guidance
GO:0031589 IDA cell-substrate adhesion
GO:0031901 IDA early endosome membrane
GO:0045121 IEA membrane raft
GO:0046328 IDA regulation of JNK cascade
GO:0046777 IDA protein autophosphorylation
GO:0048013 IEA:IDA ephrin receptor signaling pathway
GO:0048593 IEA camera-type eye morphogenesis
GO:0050965 ISS detection of temperature stimulus involved in sensory perception of pain
GO:0051965 ISS positive regulation of synapse assembly
GO:0060326 IDA cell chemotaxis
GO:0060996 ISS dendritic spine development
GO:0060997 ISS dendritic spine morphogenesis
GO:0061351 ISS neural precursor cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:0070372 IDA regulation of ERK1 and ERK2 cascade
GO:1901214 IMP regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076757 EPHB1 EPH receptor B1 protein_coding Danio_rerio
ENSMUSG00000032537 Ephb1 Eph receptor B1 protein_coding Mus_musculus

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