C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155090 KLF10 9606 - 8:102648779-102655902 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285407 KLF10-001 102648779-102655902 protein_coding
  ENST00000395884 KLF10-002 102648786-102654375 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000285407ENST00000395884
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000285407 10.246±0.00 21.583±0.00 3.629±0.00 3.455±0.84 20.074±11.39 12.600±6.11 6.655±5.03 14.124±8.84 7.674±0.91 22.050±13.50 24.637±4.94 28.750±16.44 27.054±4.76 8.662±4.22
ENST00000395884 N/A N/A N/A N/A 1.104±0.00 N/A 0.335±0.00 N/A 0.712±0.00 N/A N/A N/A N/A 7.289±2.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006A6 CIL_0006A6_0001 CGP 8:102551572-102655902
CIL_0006A7 CIL_0006A7_0001 CGP 8:102648779-102893864

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0001501 TAS skeletal system development
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007623 IEA circadian rhythm
GO:0008283 TAS cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0009267 ISS cellular response to starvation
GO:0030282 IEA bone mineralization
GO:0035019 IEA somatic stem cell maintenance
GO:0042752 ISS regulation of circadian rhythm
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037465 Klf10 Kruppel-like factor 10 protein_coding Mus_musculus

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