C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155511 GRIA1 9606 + 5:153489615-153813869 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285900 GRIA1-001 153490546-153813869 protein_coding
  ENST00000340592 GRIA1-005 153490816-153811601 protein_coding
  ENST00000448073 GRIA1-014 153492172-153811272 protein_coding
  ENST00000474198 GRIA1-002 153490644-153494334 retained_intron
  ENST00000481559 GRIA1-006 153489615-153706172 retained_intron
  ENST00000492291 GRIA1-003 153493990-153525522 processed_transcript
  ENST00000517469 GRIA1-012 153491197-153558095 processed_transcript
  ENST00000518142 GRIA1-013 153490655-153811271 protein_coding
  ENST00000518783 GRIA1-007 153492172-153813680 protein_coding
  ENST00000518862 GRIA1-009 153490482-153650507 processed_transcript
  ENST00000520353 GRIA1-008 153490268-153494065 processed_transcript
  ENST00000520966 GRIA1-011 153573228-153655865 processed_transcript
  ENST00000521843 GRIA1-010 153491297-153811619 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000285900ENST00000448073ENST00000474198ENST00000481559ENST00000517469ENST00000518142ENST00000518783ENST00000518862
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000285900 N/A 0.023±0.00 N/A 8.511±2.74 N/A N/A N/A N/A N/A N/A N/A 0.009±0.00 N/A
ENST00000448073 N/A N/A N/A N/A N/A 0.146±0.00 N/A 0.250±0.00 N/A 0.315±0.00 0.087±0.04 N/A 1.190±0.00
ENST00000474198 N/A N/A N/A N/A N/A N/A 0.158±0.00 N/A 0.710±0.00 N/A N/A 0.023±0.00 N/A
ENST00000481559 N/A N/A N/A N/A 0.092±0.00 N/A 0.023±0.00 N/A 0.235±0.00 N/A N/A 0.008±0.00 N/A
ENST00000517469 N/A 0.159±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000518142 N/A N/A N/A 4.600±0.00 N/A N/A N/A N/A N/A N/A N/A 0.068±0.00 0.298±0.00
ENST00000518783 0.396±0.00 N/A 0.037±0.00 4.590±0.00 0.064±0.02 0.142±0.00 0.060±0.00 0.086±0.00 0.058±0.00 0.127±0.00 0.073±0.06 0.021±0.01 0.155±0.00
ENST00000518862 N/A N/A N/A N/A 1.608±0.00 N/A N/A N/A N/A N/A N/A 0.065±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UF CIL_0001UF_0001 CGP 5:152391532-153813869
CIL_0001UG CIL_0001UG_0001 CGP 5:153489615-154038936

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004971 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007616 IEA long-term memory
GO:0008021 IEA synaptic vesicle
GO:0008066 TAS glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0009986 ISS cell surface
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030165 ISS PDZ domain binding
GO:0030425 ISS dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0031623 IEA receptor internalization
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032590 IEA dendrite membrane
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0043005 IEA neuron projection
GO:0043025 ISS neuronal cell body
GO:0043197 ISS dendritic spine
GO:0044308 IEA axonal spine
GO:0044309 ISS neuron spine
GO:0045211 IBA postsynaptic membrane
GO:0060292 IEA long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021352 gria1a glutamate receptor, ionotropic, AMPA 1a protein_coding Danio_rerio
ENSDARG00000032714 gria1b glutamate receptor, ionotropic, AMPA 1b protein_coding Danio_rerio
ENSMUSG00000020524 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) protein_coding Mus_musculus

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