C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase 8 (brain)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155897 ADCY8 9606 - 8:130780301-131042426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286355 ADCY8-001 130780301-131042426 protein_coding
  ENST00000377928 ADCY8-002 130780390-131040333 protein_coding
  ENST00000522949 ADCY8-003 130903772-130990865 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000286355ENST00000377928ENST00000522949
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000286355 N/A 0.619±0.22 N/A N/A N/A N/A 0.090±0.00 0.018±0.00 0.032±0.01 N/A 0.201±0.16
ENST00000377928 0.051±0.00 2.278±0.78 0.028±0.01 0.013±0.00 0.006±0.00 0.018±0.00 N/A 0.227±0.19 0.041±0.03 0.016±0.00 0.779±0.68
ENST00000522949 N/A N/A 0.026±0.00 N/A N/A N/A N/A 0.617±0.00 0.069±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004ZP CIL_0004ZP_0001 CGP 8:130052104-131042426
CIL_0006ZP CIL_0006ZP_0002 CGP 8:130780301-132013642

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004016 TAS:IEA adenylate cyclase activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IEA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007611 TAS learning or memory
GO:0007616 IEA long-term memory
GO:0008294 TAS calcium- and calmodulin-responsive adenylate cyclase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031783 adcy8 adenylate cyclase 8 (brain) protein_coding Danio_rerio
ENSMUSG00000022376 Adcy8 adenylate cyclase 8 protein_coding Mus_musculus

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