C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156427 FGF18 9606 + 5:171419656-171457623 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274625 FGF18-001 171419656-171457623 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000274625
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000274625 0.239±0.00 0.564±0.00 0.203±0.00 0.317±0.29 0.665±0.00 0.478±0.00 6.777±5.89 0.211±0.05 0.070±0.02 0.925±0.81 0.075±0.05 0.409±0.19 0.684±0.41 0.727±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088M CIL_00088M_0001 VISTA 5:170856489-171457417
CIL_00097F CIL_00097F_0001 VISTA 5:170900986-171503014
CIL_00092S CIL_00092S_0001 VISTA 5:171022159-171623481

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001525 IEA angiogenesis
GO:0001957 IEA intramembranous ossification
GO:0001958 IEA endochondral ossification
GO:0002063 IEA chondrocyte development
GO:0005105 IDA type 1 fibroblast growth factor receptor binding
GO:0005111 IDA type 2 fibroblast growth factor receptor binding
GO:0005576 TAS extracellular region
GO:0005615 TAS extracellular space
GO:0005730 IDA nucleolus
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007399 IEA nervous system development
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009653 TAS anatomical structure morphogenesis
GO:0030324 IEA lung development
GO:0030949 IEA positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043962 fgf18b fibroblast growth factor 18b protein_coding Danio_rerio
ENSDARG00000088048 fgf18a fibroblast growth factor 18a protein_coding Danio_rerio
ENSMUSG00000057967 Fgf18 fibroblast growth factor 18 protein_coding Mus_musculus

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