C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dehydrogenase/reductase (SDR family) member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157326 DHRS4 9606 + 14:23953586-23969279 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313250 DHRS4-002 23953586-23969274 protein_coding
  ENST00000397074 DHRS4-001 23953786-23969176 protein_coding
  ENST00000397075 DHRS4-003 23953779-23969009 protein_coding
  ENST00000543741 DHRS4-004 23953770-23968123 protein_coding
  ENST00000558263 DHRS4-005 23953734-23969274 protein_coding
  ENST00000558581 DHRS4-007 23953789-23969279 protein_coding
  ENST00000559632 DHRS4-006 23953789-23969274 protein_coding
  ENST00000559975 DHRS4-008 23966358-23969274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000313250ENST00000397075ENST00000543741
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000313250 N/A 2.992±0.00 1.620±0.00 N/A 2.116±0.00 0.799±0.00 12.609±0.00 5.276±4.23 N/A 4.605±0.41 6.103±5.60 5.549±1.35
ENST00000397075 14.548±0.00 N/A 2.712±0.00 16.444±0.00 17.565±0.00 6.673±0.00 15.940±0.00 N/A 9.892±0.00 N/A 6.592±0.00 10.596±3.31
ENST00000543741 N/A 1.490±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002T7 CIL_0002T7_0001 CGP 14:23630115-23969279

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000253 IDA 3-keto sterol reductase activity
GO:0004090 IDA carbonyl reductase (NADPH) activity
GO:0005102 IPI receptor binding
GO:0005634 IDA nucleus
GO:0005739 ISS mitochondrion
GO:0005777 IDA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0006066 IDA alcohol metabolic process
GO:0008152 IEA metabolic process
GO:0008202 IDA steroid metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016655 IDA oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018455 IDA alcohol dehydrogenase [NAD(P)+] activity
GO:0031965 IDA nuclear membrane
GO:0042180 IDA cellular ketone metabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051262 IDA protein tetramerization
GO:0055114 IEA:TAS oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021135 DHRS2 dehydrogenase/reductase (SDR family) member 2 protein_coding Danio_rerio
ENSMUSG00000022210 Dhrs4 dehydrogenase/reductase (SDR family) member 4 protein_coding Mus_musculus

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