C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TGF-beta activated kinase 1/MAP3K7 binding protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157625 TAB3 9606 - X:30827442-30975084 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288422 TAB3-006 30855523-30889394 protein_coding
  ENST00000378928 TAB3-003 30842988-30852887 processed_transcript
  ENST00000378930 TAB3-201 30827443-30859720 protein_coding
  ENST00000378932 TAB3-004 30830331-30975084 protein_coding
  ENST00000378933 TAB3-001 30827442-30975084 protein_coding
  ENST00000467136 TAB3-002 30834621-30871802 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378930ENST00000378932ENST00000378933ENST00000467136
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378930 2.066±0.00 1.215±0.00 1.565±0.00 3.775±0.59 1.889±0.89 1.834±0.20 1.309±0.52 4.550±0.54 2.049±0.19 0.719±0.30 1.379±0.41 2.625±1.11 1.890±0.18 3.418±1.09
ENST00000378932 N/A N/A 0.705±0.00 N/A N/A N/A N/A N/A N/A N/A 0.770±0.00 N/A N/A N/A
ENST00000378933 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.390±0.08 N/A N/A 0.680±0.00 N/A
ENST00000467136 N/A N/A N/A N/A 0.358±0.00 0.341±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007249 TAS I-kappaB kinase/NF-kappaB signaling
GO:0007254 TAS JNK cascade
GO:0008270 IEA zinc ion binding
GO:0010008 TAS endosome membrane
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0045087 TAS innate immune response
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062063 tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 protein_coding Danio_rerio
ENSMUSG00000035476 Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 protein_coding Mus_musculus

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