C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptide peptidase like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157837 SPPL3 9606 - 12:120762510-120904371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000353487 SPPL3-001 120762510-120904371 protein_coding
  ENST00000392495 SPPL3-002 120764465-120770137 retained_intron
  ENST00000534966 SPPL3-007 120784203-120791945 retained_intron
  ENST00000536996 SPPL3-003 120768438-120903494 protein_coding
  ENST00000540091 SPPL3-008 120784474-120811442 protein_coding
  ENST00000543181 SPPL3-006 120782690-120835657 protein_coding
  ENST00000543608 SPPL3-005 120768958-120903370 protein_coding
  ENST00000543854 SPPL3-009 120768997-120903370 protein_coding
  ENST00000545209 SPPL3-004 120764891-120768631 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000353487ENST00000392495ENST00000543854ENST00000545209
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000353487 8.448±0.00 5.087±0.00 8.318±0.00 8.578±0.00 1.800±0.00 5.993±0.00 9.911±0.00 2.135±0.00 5.106±0.00 5.119±0.00 8.038±5.59 7.631±6.76 10.602±5.84
ENST00000392495 2.978±0.00 2.624±0.00 N/A 1.633±0.00 1.572±0.00 N/A N/A 0.927±0.00 1.500±0.63 0.594±0.00 3.662±0.00 N/A 10.335±0.00
ENST00000543854 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.387±0.00 N/A N/A N/A
ENST00000545209 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.708±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZA CIL_0007ZA_0001 VISTA 12:120240385-120840841

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005791 IDA rough endoplasmic reticulum
GO:0006508 IEA proteolysis
GO:0016021 IEA integral component of membrane
GO:0030660 IDA Golgi-associated vesicle membrane
GO:0042500 IMP aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 IDA protein homodimerization activity
GO:0071458 IDA integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 IDA integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025220 sppl3 signal peptide peptidase 3 protein_coding Danio_rerio
ENSMUSG00000029550 Sppl3 signal peptide peptidase 3 protein_coding Mus_musculus

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