C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 4-hydroxyphenylpyruvate dioxygenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158104 HPD 9606 - 12:121839527-121863596 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289004 HPD-002 121839527-121858859 protein_coding
  ENST00000535114 HPD-003 121856598-121858855 retained_intron
  ENST00000542159 HPD-004 121848990-121857583 retained_intron
  ENST00000543163 HPD-001 121839530-121863596 protein_coding
  ENST00000543869 HPD-005 121846862-121849791 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000289004ENST00000542159ENST00000543163ENST00000543869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000289004 0.021±0.00 1.371±0.00 35.589±0.00 0.736±0.58 1.437±0.56 0.624±0.00 0.103±0.00 241.574±179.18 367.023±366.67 0.323±0.00 0.424±0.00 1.404±1.64 0.810±0.61 3.409±0.23
ENST00000542159 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.448±0.00 N/A N/A N/A N/A
ENST00000543163 N/A 0.356±0.00 N/A N/A 0.528±0.00 N/A N/A N/A N/A 0.328±0.00 N/A N/A 0.134±0.00 1.489±0.00
ENST00000543869 0.139±0.00 N/A N/A N/A N/A 0.427±0.00 0.480±0.00 N/A N/A N/A N/A 0.099±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZI CIL_0002ZI_0001 CGP 12:121804180-121863596
CIL_0002ZH CIL_0002ZH_0001 CGP 12:121839527-121918297

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0003868 IEA 4-hydroxyphenylpyruvate dioxygenase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0006559 IEA L-phenylalanine catabolic process
GO:0006572 ISS tyrosine catabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016701 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044935 hpdb 4-hydroxyphenylpyruvate dioxygenase b protein_coding Danio_rerio
ENSMUSG00000029445 Hpd 4-hydroxyphenylpyruvic acid dioxygenase protein_coding Mus_musculus

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