C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158417 EIF5B 9606 + 2:99337353-99401326 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289371 EIF5B-001 99337353-99401326 protein_coding
  ENST00000470023 EIF5B-002 99397047-99399774 retained_intron
  ENST00000470868 EIF5B-003 99389607-99390690 retained_intron
  ENST00000494190 EIF5B-004 99394809-99399197 retained_intron
  ENST00000617677 EIF5B-201 99337371-99400265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000289371ENST00000617677
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000289371 N/A N/A N/A 0.668±0.00 1.348±0.00 N/A N/A 1.006±0.00 1.276±0.00 1.634±0.00 0.805±0.00 7.559±6.11 9.980±0.00
ENST00000617677 17.167±0.00 15.833±0.00 1.184±0.00 10.814±0.00 2.032±0.00 1.274±0.00 7.714±7.04 N/A N/A N/A N/A 9.719±5.51 4.223±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000349 CIL_000349_0001 CGP 2:99284238-99340702
CIL_000348 CIL_000348_0001 CGP 2:99318982-99401326
CIL_000347 CIL_000347_0001 CGP 2:99337353-99490035

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 NAS translation initiation factor activity
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0006446 NAS regulation of translational initiation
GO:0010467 TAS gene expression
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016548 eif5b eukaryotic translation initiation factor 5B protein_coding Danio_rerio
ENSMUSG00000026083 Eif5b eukaryotic translation initiation factor 5B protein_coding Mus_musculus

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