C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin, alpha, cardiac muscle 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159251 ACTC1 9606 - 15:34788096-34796139 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290378 ACTC1-001 34788096-34796139 protein_coding
  ENST00000557860 ACTC1-003 34791158-34792851 processed_transcript
  ENST00000560563 ACTC1-004 34791701-34792522 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290378ENST00000557860
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290378 0.512±0.00 1.828±0.00 0.029±0.00 0.145±0.00 0.222±0.07 0.223±0.20 487.553±367.86 1.463±0.00 8.394±8.29 1.834±0.26 16.303±11.93 0.223±0.12 1.676±1.12 6.058±5.92
ENST00000557860 1.066±0.00 6.779±0.00 N/A 0.309±0.00 0.846±0.47 0.964±0.00 1216.198±948.33 4.795±0.00 27.069±26.90 4.392±0.00 74.246±0.00 0.635±0.21 3.290±0.37 15.083±14.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VH CIL_0008VH_0001 VISTA 15:34591431-35191947
CIL_0005II CIL_0005II_0002 CGP 15:34751032-34796139
CIL_0006HF CIL_0006HF_0001 CGP 15:34788096-34969839

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006915 ISS apoptotic process
GO:0016020 IDA membrane
GO:0016887 IDA ATPase activity
GO:0017022 IPI myosin binding
GO:0030017 IDA sarcomere
GO:0030048 IDA actin filament-based movement
GO:0030049 TAS muscle filament sliding
GO:0030240 ISS skeletal muscle thin filament assembly
GO:0031032 ISS actomyosin structure organization
GO:0031674 ISS I band
GO:0033275 IMP actin-myosin filament sliding
GO:0042493 IEA response to drug
GO:0042643 IDA actomyosin, actin portion
GO:0043066 IEA negative regulation of apoptotic process
GO:0045471 IEA response to ethanol
GO:0055003 ISS cardiac myofibril assembly
GO:0055008 ISS cardiac muscle tissue morphogenesis
GO:0060047 IMP heart contraction
GO:0060048 IEA cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0070252 IEA actin-mediated cell contraction
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036371 acta1a actin, alpha 1a, skeletal muscle protein_coding Danio_rerio
ENSDARG00000037840 actc1b actin, alpha, cardiac muscle 1b protein_coding Danio_rerio
ENSDARG00000042535 actc1a actin, alpha, cardiac muscle 1a protein_coding Danio_rerio
ENSDARG00000055618 acta1b actin, alpha 1b, skeletal muscle protein_coding Danio_rerio
ENSDARG00000057911 actin, alpha, cardiac muscle 1 protein_coding Danio_rerio
ENSDARG00000076126 hm:zewp0073 actin, alpha, cardiac muscle 1 protein_coding Danio_rerio
ENSMUSG00000068614 Actc1 actin, alpha, cardiac muscle 1 protein_coding Mus_musculus

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