C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hexokinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159399 HK2 9606 + 2:74833981-74893359 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290573 HK2-001 74833981-74893359 protein_coding
  ENST00000409174 HK2-002 74835170-74893359 protein_coding
  ENST00000472302 HK2-003 74854333-74867907 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290573ENST00000409174
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290573 2.409±0.00 1.806±0.00 N/A 1.793±0.00 14.174±12.56 1.927±0.72 4.274±0.00 0.413±0.00 0.455±0.19 3.559±0.00 5.660±0.09 4.005±1.69 4.018±4.01 6.804±1.78
ENST00000409174 2.888±0.00 N/A 0.361±0.00 0.789±0.08 8.955±8.34 4.226±2.25 0.891±0.00 0.236±0.19 0.380±0.33 1.192±0.58 1.624±0.00 4.917±2.40 2.607±0.99 13.562±2.98

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001678 IBA cellular glucose homeostasis
GO:0002931 IEA response to ischemia
GO:0004340 IBA glucokinase activity
GO:0004396 TAS hexokinase activity
GO:0005524 IEA ATP binding
GO:0005536 IEA glucose binding
GO:0005739 IEA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0005975 TAS:IEA carbohydrate metabolic process
GO:0006006 IEA glucose metabolic process
GO:0006096 IEA:IBA glycolytic process
GO:0007595 IEA lactation
GO:0008637 IDA apoptotic mitochondrial changes
GO:0008645 TAS hexose transport
GO:0008865 IBA fructokinase activity
GO:0015758 TAS glucose transport
GO:0016020 IDA membrane
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0019158 IBA mannokinase activity
GO:0044281 TAS small molecule metabolic process
GO:0046324 IEA regulation of glucose import
GO:0046835 IEA carbohydrate phosphorylation
GO:0051156 IBA glucose 6-phosphate metabolic process
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026964 hk2 hexokinase 2 protein_coding Danio_rerio
ENSMUSG00000000628 Hk2 hexokinase 2 protein_coding Mus_musculus

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