C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calmodulin 3 (phosphorylase kinase, delta)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160014 CALM3 9606 + 19:46601074-46610793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291295 CALM3-001 46601236-46610793 protein_coding
  ENST00000391918 CALM3-009 46601074-46609305 protein_coding
  ENST00000477244 CALM3-005 46601309-46609275 processed_transcript
  ENST00000482455 CALM3-004 46605193-46609243 processed_transcript
  ENST00000486500 CALM3-002 46607962-46610781 retained_intron
  ENST00000594523 CALM3-015 46601366-46609182 protein_coding
  ENST00000595072 CALM3-012 46607973-46609234 retained_intron
  ENST00000596362 CALM3-003 46602072-46609770 protein_coding
  ENST00000597743 CALM3-013 46601276-46609319 protein_coding
  ENST00000597868 CALM3-011 46601367-46609305 retained_intron
  ENST00000598871 CALM3-014 46601330-46609190 protein_coding
  ENST00000599839 CALM3-007 46602069-46609996 protein_coding
  ENST00000602169 CALM3-010 46601364-46606342 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000291295ENST00000391918ENST00000477244ENST00000482455ENST00000594523ENST00000596362ENST00000597743ENST00000599839
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000291295 6.679±0.00 184.513±0.00 10.738±0.00 14.616±0.00 5.918±0.00 19.625±0.00 18.287±0.00 5.896±0.00 3.763±0.00 82.258±97.75 64.746±21.03 131.022±0.00
ENST00000391918 N/A N/A 11.291±0.00 10.129±0.00 N/A N/A 26.160±0.00 12.365±0.00 N/A 4.941±0.00 N/A 204.238±0.00
ENST00000477244 7.541±0.00 N/A 62.141±0.00 N/A N/A N/A N/A N/A 15.950±0.00 N/A N/A 160.164±0.00
ENST00000482455 N/A 178.294±0.00 N/A 12.430±0.00 8.705±0.00 15.814±0.00 N/A 7.126±0.00 N/A 8.919±0.00 N/A N/A
ENST00000594523 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.764±0.00 N/A N/A
ENST00000596362 5.792±0.00 N/A N/A N/A 8.002±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000597743 N/A 700.767±0.00 N/A N/A 83.317±0.00 N/A N/A N/A 30.460±21.80 N/A N/A 125.114±0.00
ENST00000599839 N/A N/A N/A N/A N/A 44.217±0.00 N/A N/A 4.994±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0001975 IEA response to amphetamine
GO:0002027 IMP regulation of heart rate
GO:0002576 TAS platelet degranulation
GO:0005509 ISS:IEA calcium ion binding
GO:0005513 IMP detection of calcium ion
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005876 IDA spindle microtubule
GO:0005886 TAS plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0005980 TAS glycogen catabolic process
GO:0006006 TAS glucose metabolic process
GO:0006936 TAS muscle contraction
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007190 IEA activation of adenylate cyclase activity
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0008179 IEA adenylate cyclase binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010800 TAS positive regulation of peptidyl-threonine phosphorylation
GO:0010801 TAS negative regulation of peptidyl-threonine phosphorylation
GO:0010880 IDA regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IC regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0019722 IEA calcium-mediated signaling
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0021762 IEP substantia nigra development
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0030017 IDA sarcomere
GO:0030168 TAS platelet activation
GO:0030234 IEA enzyme regulator activity
GO:0030235 IEA nitric-oxide synthase regulator activity
GO:0030426 IEA growth cone
GO:0030801 IDA positive regulation of cyclic nucleotide metabolic process
GO:0031432 IPI titin binding
GO:0031800 IEA type 3 metabotropic glutamate receptor binding
GO:0031954 TAS positive regulation of protein autophosphorylation
GO:0031982 IDA vesicle
GO:0031996 IPI thioesterase binding
GO:0031997 IPI N-terminal myristoylation domain binding
GO:0032465 IMP regulation of cytokinesis
GO:0032516 IDA positive regulation of phosphoprotein phosphatase activity
GO:0034704 IDA calcium channel complex
GO:0035307 IDA positive regulation of protein dephosphorylation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043274 IPI phospholipase binding
GO:0043539 TAS protein serine/threonine kinase activator activity
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044325 IPI ion channel binding
GO:0045087 TAS innate immune response
GO:0046209 TAS nitric oxide metabolic process
GO:0047485 IEA protein N-terminus binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048306 IEA calcium-dependent protein binding
GO:0050998 IEA nitric-oxide synthase binding
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0051343 IDA positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051412 IEA response to corticosterone
GO:0051592 IDA response to calcium ion
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060314 IEA regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 ISS negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 IDA positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0071902 TAS positive regulation of protein serine/threonine kinase activity
GO:0072542 IDA protein phosphatase activator activity
GO:1901841 IEA regulation of high voltage-gated calcium channel activity
GO:1901844 IC regulation of cell communication by electrical coupling involved in cardiac conduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031427 calm3b calmodulin 3b (phosphorylase kinase, delta) protein_coding Danio_rerio
ENSMUSG00000019370 Calm3 calmodulin 3 protein_coding Mus_musculus

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