C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA fragmentation factor, 45kDa, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160049 DFFA 9606 - 1:10456522-10472526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377036 DFFA-002 10462468-10472488 protein_coding
  ENST00000377038 DFFA-001 10456522-10472526 protein_coding
  ENST00000476658 DFFA-003 10461643-10472479 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377036ENST00000377038ENST00000476658
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377036 N/A N/A N/A 2.867±0.00 1.986±0.00 2.693±0.00 1.308±0.00 2.158±0.00 N/A 3.195±0.00 3.194±0.00 N/A 8.951±1.63 N/A
ENST00000377038 5.114±0.00 3.489±0.00 1.181±0.00 2.679±1.20 3.124±1.26 3.799±2.37 1.586±0.63 2.388±1.14 2.503±0.00 1.491±0.22 1.952±1.07 8.114±3.06 6.233±2.42 5.536±0.11
ENST00000476658 N/A N/A N/A N/A N/A N/A N/A 3.470±0.00 N/A N/A N/A 32.327±0.00 15.237±0.00 10.097±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008IM CIL_0008IM_0001 VISTA 1:10233066-10834152
CIL_0007WE CIL_0007WE_0001 VISTA 1:10372013-10973061
CIL_00085P CIL_00085P_0001 VISTA 1:10397607-10998574
CIL_00082Y CIL_00082Y_0001 VISTA 1:10421182-11021687
CIL_0008S2 CIL_0008S2_0001 VISTA 1:10435049-11039184
CIL_00019O CIL_00019O_0002 CGP 1:10456522-10630758

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006915 TAS:IEA apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007165 IEA signal transduction
GO:0043065 IEA positive regulation of apoptotic process
GO:0070242 IEA thymocyte apoptotic process
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:1902511 IDA negative regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055770 dffa DNA fragmentation factor, alpha polypeptide protein_coding Danio_rerio
ENSMUSG00000028974 Dffa DNA fragmentation factor, alpha subunit protein_coding Mus_musculus

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