C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inducible T-cell co-stimulator ligand
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160223 ICOSLG 9606 - 21:44222991-44240966 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344330 ICOSLG-003 44222991-44240840 protein_coding
  ENST00000400377 ICOSLG-002 44226834-44240966 protein_coding
  ENST00000400379 ICOSLG-004 44226834-44240945 protein_coding
  ENST00000407780 ICOSLG-001 44222991-44240945 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000400377ENST00000400379ENST00000407780
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000400377 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.047±0.00 N/A N/A N/A N/A
ENST00000400379 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.058±0.00 0.119±0.00 0.100±0.03 N/A
ENST00000407780 1.056±0.00 1.111±0.00 0.191±0.00 3.029±0.00 0.363±0.27 0.266±0.16 0.348±0.34 1.254±1.22 0.244±0.18 0.532±0.43 0.097±0.09 0.691±0.42 0.495±0.13 0.860±0.59

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006952 NAS defense response
GO:0006972 NAS hyperosmotic response
GO:0007165 NAS signal transduction
GO:0016021 NAS integral component of membrane
GO:0031295 TAS T cell costimulation
GO:0042104 TAS positive regulation of activated T cell proliferation
GO:0042110 NAS T cell activation
GO:0042113 IEA B cell activation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000000732 Icosl icos ligand protein_coding Mus_musculus

Loading