C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proprotein convertase subtilisin/kexin type 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160613 PCSK7 9606 - 11:117204337-117232525 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320934 PCSK7-001 117204337-117232525 protein_coding
  ENST00000524507 PCSK7-007 117229506-117231868 protein_coding
  ENST00000525027 PCSK7-004 117224700-117230240 protein_coding
  ENST00000527037 PCSK7-009 117206148-117220138 retained_intron
  ENST00000527861 PCSK7-013 117206680-117208681 retained_intron
  ENST00000528217 PCSK7-008 117219124-117223063 retained_intron
  ENST00000528973 PCSK7-011 117208673-117218464 retained_intron
  ENST00000529458 PCSK7-015 117205947-117208136 processed_transcript
  ENST00000530269 PCSK7-005 117229570-117232525 protein_coding
  ENST00000531573 PCSK7-014 117207693-117208488 retained_intron
  ENST00000532301 PCSK7-006 117229567-117232074 protein_coding
  ENST00000532810 PCSK7-012 117206774-117209365 retained_intron
  ENST00000533135 PCSK7-010 117207775-117219165 processed_transcript
  ENST00000534529 PCSK7-003 117205074-117226876 retained_intron
  ENST00000540028 PCSK7-201 117205078-117232095 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000320934ENST00000528973
Transcript ID Bladder Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000320934 1.801±0.00 3.986±3.33 16.757±1.99 12.525±0.00 2.543±1.68 14.207±0.00 3.604±0.00 5.405±1.92 14.537±2.87 7.092±0.00
ENST00000528973 N/A N/A N/A N/A 0.219±0.00 0.221±0.00 N/A 1.616±0.65 N/A 3.670±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RC CIL_0007RC_0001 VISTA 11:116660805-117262910

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA:IBA serine-type endopeptidase activity
GO:0006508 IEA proteolysis
GO:0008233 IDA peptidase activity
GO:0016485 IDA protein processing
GO:0016486 NAS peptide hormone processing
GO:0030173 IDA integral component of Golgi membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069968 pcsk7 proprotein convertase subtilisin/kexin type 7 protein_coding Danio_rerio
ENSMUSG00000035382 Pcsk7 proprotein convertase subtilisin/kexin type 7 protein_coding Mus_musculus

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