C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 3, subfamily A, polypeptide 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160870 CYP3A7 9606 - 7:99684679-99735196 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336374 CYP3A7-001 99705044-99735096 protein_coding
  ENST00000467776 CYP3A7-003 99730573-99735196 retained_intron
  ENST00000477357 CYP3A7-002 99705037-99720969 retained_intron
  ENST00000498080 CYP3A7-004 99715348-99717265 retained_intron
  ENST00000611620 CYP3A7-201 99684679-99735196 protein_coding
  ENST00000620220 CYP3A7-202 99684957-99735102 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336374ENST00000467776ENST00000477357ENST00000498080ENST00000611620ENST00000620220
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336374 0.065±0.00 0.065±0.00 1.120±0.00 0.021±0.00 N/A 0.038±0.00 0.062±0.04 3.455±3.19 2.773±0.00 0.315±0.00 0.158±0.00 0.085±0.00 0.393±0.39 0.048±0.02
ENST00000467776 N/A N/A N/A 0.069±0.00 N/A N/A N/A N/A 0.187±0.00 N/A N/A N/A 0.076±0.00 N/A
ENST00000477357 N/A N/A N/A N/A N/A N/A N/A N/A 0.293±0.13 N/A N/A N/A N/A N/A
ENST00000498080 N/A N/A N/A 0.512±0.00 0.996±0.00 N/A 0.182±0.00 N/A 0.538±0.00 0.783±0.00 N/A 0.074±0.03 N/A N/A
ENST00000611620 N/A N/A N/A 0.077±0.00 0.144±0.09 0.132±0.00 N/A N/A N/A N/A N/A 0.018±0.00 N/A 0.037±0.00
ENST00000620220 N/A N/A N/A N/A N/A 0.093±0.00 N/A N/A N/A N/A 0.295±0.00 N/A N/A 0.015±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005LC CIL_0005LC_0004 CGP 7:99648194-99735196
CIL_0005LC CIL_0005LC_0006 CGP 7:99684679-99784265

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 ISS monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825 TAS oxygen binding
GO:0020037 IEA heme binding
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070330 IEA aromatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015575 cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000037873 cyp3c1l2 cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2 protein_coding Danio_rerio
ENSDARG00000037874 si:dkey-21n8.3 si:dkey-21n8.3 protein_coding Danio_rerio
ENSDARG00000045627 cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 protein_coding Danio_rerio
ENSDARG00000070021 cyp3c4 cytochrome P450, family 3, subfamily C, polypeptide 4 protein_coding Danio_rerio
ENSMUSG00000029630 Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 protein_coding Mus_musculus
ENSMUSG00000029727 Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 protein_coding Mus_musculus
ENSMUSG00000038656 Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 protein_coding Mus_musculus
ENSMUSG00000054417 Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 protein_coding Mus_musculus
ENSMUSG00000056035 Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 protein_coding Mus_musculus
ENSMUSG00000061292 Cyp3a59 cytochrome P450, family 3, subfamily a, polypeptide 59 protein_coding Mus_musculus
ENSMUSG00000070419 Cyp3a57 cytochrome P450, family 3, subfamily a, polypeptide 57 protein_coding Mus_musculus
ENSMUSG00000075551 Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A protein_coding Mus_musculus
ENSMUSG00000075552 Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B protein_coding Mus_musculus

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