C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidoglycan recognition protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161031 PGLYRP2 9606 - 19:15468645-15498956 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292609 PGLYRP2-002 15468645-15479501 protein_coding
  ENST00000340880 PGLYRP2-001 15468645-15479852 protein_coding
  ENST00000594637 PGLYRP2-004 15476353-15479831 protein_coding
  ENST00000601792 PGLYRP2-003 15476235-15498956 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLungOvaryTestisENST00000292609ENST00000340880
Transcript ID Adrenal Brain Breast Heart Kidney Lung Ovary Testis
ENST00000292609 N/A N/A N/A 0.033±0.00 N/A 0.015±0.00 N/A 0.479±0.31
ENST00000340880 0.126±0.00 0.025±0.00 0.080±0.04 N/A 5.118±0.00 N/A 0.028±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019W CIL_00019W_0001 CGP 19:15451624-15498956
CIL_0001MH CIL_0001MH_0001 CGP 19:15468645-15552317

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001519 NAS peptide amidation
GO:0002221 IDA pattern recognition receptor signaling pathway
GO:0005622 NAS intracellular
GO:0008270 IEA zinc ion binding
GO:0008745 IEA:TAS N-acetylmuramoyl-L-alanine amidase activity
GO:0009253 IEA peptidoglycan catabolic process
GO:0016019 IDA peptidoglycan receptor activity
GO:0016020 NAS membrane
GO:0016045 IDA detection of bacterium
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032827 IEA negative regulation of natural killer cell differentiation involved in immune response
GO:0042834 IDA peptidoglycan binding
GO:0044117 IEA growth of symbiont in host
GO:0045087 NAS innate immune response
GO:0050727 IEA regulation of inflammatory response
GO:0050830 IDA defense response to Gram-positive bacterium
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015626 pglyrp6 peptidoglycan recognition protein 6 protein_coding Danio_rerio
ENSDARG00000062998 pglyrp2 peptidoglycan recognition protein 2 protein_coding Danio_rerio
ENSMUSG00000079563 Pglyrp2 peptidoglycan recognition protein 2 protein_coding Mus_musculus

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