C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161960 EIF4A1 9606 + 17:7572706-7579005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293831 EIF4A1-001 7572826-7579005 protein_coding
  ENST00000396527 EIF4A1-003 7572826-7578401 retained_intron
  ENST00000577269 EIF4A1-007 7572837-7578641 protein_coding
  ENST00000577731 EIF4A1-034 7575188-7577567 retained_intron
  ENST00000577738 EIF4A1-016 7573433-7575352 retained_intron
  ENST00000577929 EIF4A1-018 7573844-7575216 protein_coding
  ENST00000578324 EIF4A1-009 7574259-7578616 retained_intron
  ENST00000578476 EIF4A1-014 7572826-7576587 nonsense_mediated_decay
  ENST00000578495 EIF4A1-026 7572826-7577706 protein_coding
  ENST00000578569 EIF4A1-029 7577148-7577931 retained_intron
  ENST00000578754 EIF4A1-023 7572826-7577682 protein_coding
  ENST00000579085 EIF4A1-019 7572828-7575077 retained_intron
  ENST00000579139 EIF4A1-013 7572827-7575320 nonsense_mediated_decay
  ENST00000580461 EIF4A1-002 7572826-7575658 nonsense_mediated_decay
  ENST00000580886 EIF4A1-012 7572826-7574782 retained_intron
  ENST00000580888 EIF4A1-038 7572706-7577115 nonsense_mediated_decay
  ENST00000581384 EIF4A1-037 7573722-7577151 protein_coding
  ENST00000581544 EIF4A1-004 7572828-7578467 nonsense_mediated_decay
  ENST00000581770 EIF4A1-015 7573316-7575165 protein_coding
  ENST00000581808 EIF4A1-033 7577687-7578195 processed_transcript
  ENST00000581841 EIF4A1-035 7577566-7578306 retained_intron
  ENST00000582050 EIF4A1-032 7577635-7578630 nonsense_mediated_decay
  ENST00000582169 EIF4A1-024 7572826-7576690 protein_coding
  ENST00000582213 EIF4A1-021 7572828-7575508 retained_intron
  ENST00000582746 EIF4A1-008 7572842-7578990 protein_coding
  ENST00000582848 EIF4A1-027 7572828-7576761 retained_intron
  ENST00000583217 EIF4A1-030 7577207-7577886 retained_intron
  ENST00000583389 EIF4A1-031 7576532-7578631 protein_coding
  ENST00000583802 EIF4A1-022 7572828-7577139 protein_coding
  ENST00000583899 EIF4A1-020 7572828-7576732 retained_intron
  ENST00000584054 EIF4A1-011 7572824-7575171 retained_intron
  ENST00000584712 EIF4A1-036 7572826-7575679 retained_intron
  ENST00000584784 EIF4A1-028 7572838-7577704 protein_coding
  ENST00000584798 EIF4A1-010 7574746-7576185 retained_intron
  ENST00000584860 EIF4A1-017 7573235-7577619 protein_coding
  ENST00000584901 EIF4A1-006 7572828-7577363 retained_intron
  ENST00000585024 EIF4A1-025 7572828-7577110 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000293831ENST00000577269ENST00000577731ENST00000578569ENST00000580888ENST00000585024
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000293831 190.545±0.00 206.581±0.00 12.342±0.00 51.090±26.26 73.793±46.97 75.205±35.43 33.716±24.20 120.687±102.54 78.738±50.62 145.382±111.12 40.164±26.21 187.209±104.11 264.846±80.85 90.043±35.59
ENST00000577269 N/A N/A N/A N/A N/A 58.179±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000577731 N/A N/A 40.487±0.00 73.198±0.00 84.047±0.00 160.366±0.00 35.167±0.00 64.355±0.00 95.474±0.00 N/A 44.642±0.00 191.541±0.00 N/A N/A
ENST00000578569 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 281.062±0.00 403.006±0.00 129.857±0.00
ENST00000580888 N/A N/A N/A N/A N/A N/A N/A N/A 84.423±0.00 N/A N/A N/A N/A N/A
ENST00000585024 N/A N/A 43.681±0.00 N/A 98.990±0.00 N/A N/A 74.209±0.00 N/A 138.210±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00037A CIL_00037A_0002 CGP 17:7561875-7578715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000339 TAS RNA cap binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0003729 TAS mRNA binding
GO:0003743 IEA translation initiation factor activity
GO:0004386 TAS helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006200 IEA ATP catabolic process
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0008026 IEA ATP-dependent helicase activity
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016281 TAS eukaryotic translation initiation factor 4F complex
GO:0016787 IEA hydrolase activity
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031100 IEA organ regeneration
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000059796 Eif4a1 eukaryotic translation initiation factor 4A1 protein_coding Mus_musculus

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