C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell acute lymphocytic leukemia 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162367 TAL1 9606 - 1:47216290-47232220 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294339 TAL1-002 47216292-47229771 protein_coding
  ENST00000371884 TAL1-001 47216290-47231715 protein_coding
  ENST00000459729 TAL1-004 47218688-47224076 processed_transcript
  ENST00000464796 TAL1-003 47224072-47232220 processed_transcript
  ENST00000465912 TAL1-006 47228348-47229453 processed_transcript
  ENST00000481091 TAL1-005 47228347-47231218 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371884ENST00000459729
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371884 2.851±0.00 1.618±0.00 0.239±0.00 0.390±0.07 0.481±0.04 0.144±0.00 0.810±0.65 0.732±0.50 0.511±0.00 5.014±0.00 0.088±0.00 0.637±0.36 2.529±0.17 0.779±0.00
ENST00000459729 N/A N/A 0.263±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.662±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001525 IEA angiogenesis
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007626 IEA locomotory behavior
GO:0019899 IPI enzyme binding
GO:0021527 IEA spinal cord association neuron differentiation
GO:0030097 ISS hemopoiesis
GO:0030099 IEA myeloid cell differentiation
GO:0030182 IEA neuron differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030219 IEP megakaryocyte differentiation
GO:0030220 IEA platelet formation
GO:0030221 IEP basophil differentiation
GO:0031334 IDA positive regulation of protein complex assembly
GO:0033193 IDA Lsd1/2 complex
GO:0035162 ISS embryonic hemopoiesis
GO:0035855 IEA megakaryocyte development
GO:0042127 IEA regulation of cell proliferation
GO:0042826 IPI histone deacetylase binding
GO:0043234 IEA protein complex
GO:0043249 IEA erythrocyte maturation
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045165 ISS cell fate commitment
GO:0045637 IEA regulation of myeloid cell differentiation
GO:0045648 ISS positive regulation of erythrocyte differentiation
GO:0045799 IMP positive regulation of chromatin assembly or disassembly
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048699 IEA generation of neurons
GO:0051781 IMP positive regulation of cell division
GO:0060018 IEA astrocyte fate commitment
GO:0060216 IEA definitive hemopoiesis
GO:0060217 IEA hemangioblast cell differentiation
GO:0060218 IEA hematopoietic stem cell differentiation
GO:0060375 IEA regulation of mast cell differentiation
GO:0070888 IDA E-box binding
GO:2000036 IEA regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019930 tal1 T-cell acute lymphocytic leukemia 1 protein_coding Danio_rerio
ENSMUSG00000028717 Tal1 T cell acute lymphocytic leukemia 1 protein_coding Mus_musculus

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