C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidic acid phosphatase type 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162407 PPAP2B 9606 - 1:56494747-56645301 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371250 PPAP2B-001 56494747-56579568 protein_coding
  ENST00000459962 PPAP2B-002 56496434-56513771 processed_transcript
  ENST00000461655 PPAP2B-004 56524308-56645301 processed_transcript
  ENST00000472957 PPAP2B-003 56496276-56517006 processed_transcript
  ENST00000476206 PPAP2B-005 56579168-56645272 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371250ENST00000459962
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371250 46.462±0.00 27.256±0.00 14.415±0.00 29.739±15.05 20.407±8.76 25.565±18.93 18.911±10.65 38.483±11.35 28.936±2.20 48.561±30.64 7.930±4.16 30.407±24.39 75.858±4.24 52.439±39.70
ENST00000459962 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.397±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Q8 CIL_0007Q8_0001 VISTA 1:55987109-56588315
CIL_00005E CIL_00005E_0002 CGP 1:56494747-56715335

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IEA blood vessel development
GO:0001702 IEA gastrulation with mouth forming second
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0003824 IEA catalytic activity
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005794 IEA Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005912 TAS adherens junction
GO:0006629 NAS lipid metabolic process
GO:0006644 IEA phospholipid metabolic process
GO:0006665 TAS sphingolipid metabolic process
GO:0007155 IEA cell adhesion
GO:0008195 IEA phosphatidate phosphatase activity
GO:0008354 TAS germ cell migration
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016337 IEA single organismal cell-cell adhesion
GO:0030111 IEA regulation of Wnt signaling pathway
GO:0030148 TAS sphingolipid biosynthetic process
GO:0034109 IDA homotypic cell-cell adhesion
GO:0042392 IEA sphingosine-1-phosphate phosphatase activity
GO:0042577 IEA lipid phosphatase activity
GO:0044281 TAS small molecule metabolic process
GO:0044328 IMP canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
GO:0044329 IMP canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
GO:0044330 IMP canonical Wnt signaling pathway involved in positive regulation of wound healing
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050821 IDA protein stabilization
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060020 IEA Bergmann glial cell differentiation
GO:0060070 IEA canonical Wnt signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:1902068 IEA regulation of sphingolipid mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059933 ppap2b phosphatidic acid phosphatase type 2B protein_coding Danio_rerio
ENSMUSG00000028517 Ppap2b phosphatidic acid phosphatase type 2B protein_coding Mus_musculus

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