C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkaline phosphatase, liver/bone/kidney
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162551 ALPL 9606 + 1:21509372-21578412 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374829 ALPL-003 21574478-21578399 processed_transcript
  ENST00000374830 ALPL-004 21570303-21577731 protein_coding
  ENST00000374832 ALPL-002 21551279-21578012 protein_coding
  ENST00000374840 ALPL-001 21509372-21578412 protein_coding
  ENST00000468526 ALPL-005 21509397-21564211 processed_transcript
  ENST00000539907 ALPL-006 21509426-21578399 protein_coding
  ENST00000540617 ALPL-007 21509428-21578175 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374829ENST00000374832ENST00000374840ENST00000468526ENST00000539907ENST00000540617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374829 N/A N/A N/A 0.405±0.00 N/A N/A N/A N/A N/A N/A 0.317±0.00 N/A 3.062±0.00 N/A
ENST00000374832 N/A N/A N/A N/A N/A N/A 0.223±0.00 0.677±0.00 N/A N/A N/A N/A N/A N/A
ENST00000374840 15.767±0.00 4.462±0.00 0.600±0.00 2.660±2.16 1.950±1.61 1.938±0.00 2.506±2.39 5.407±0.00 17.179±0.00 8.429±5.44 0.526±0.00 2.535±0.25 1.811±0.67 2.843±0.24
ENST00000468526 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.073±0.00 N/A N/A N/A
ENST00000539907 12.356±0.00 7.669±0.00 N/A N/A 3.703±0.00 2.392±0.00 N/A 10.819±0.00 12.387±0.00 7.892±0.00 N/A 1.985±0.81 2.366±0.26 3.654±0.27
ENST00000540617 27.530±0.00 7.509±0.00 N/A 8.098±0.00 3.605±0.00 5.847±0.00 1.725±0.00 N/A 4.074±3.99 7.770±0.00 N/A 1.781±0.00 N/A 4.351±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001649 IDA osteoblast differentiation
GO:0001958 IEA endochondral ossification
GO:0003006 IEA developmental process involved in reproduction
GO:0003824 IEA catalytic activity
GO:0004035 IEA alkaline phosphatase activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0008152 IEA metabolic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016462 IDA pyrophosphatase activity
GO:0016791 IEA phosphatase activity
GO:0031012 IEA extracellular matrix
GO:0031225 IEA anchored component of membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0033280 IEP response to vitamin D
GO:0046677 IEA response to antibiotic
GO:0046872 IEA metal ion binding
GO:0051384 IEA response to glucocorticoid
GO:0065010 IEA extracellular membrane-bounded organelle
GO:0070062 IDA extracellular vesicular exosome
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071529 IEA cementum mineralization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015546 alpl alkaline phosphatase, liver/bone/kidney protein_coding Danio_rerio
ENSMUSG00000028766 Alpl alkaline phosphatase, liver/bone/kidney protein_coding Mus_musculus

Loading