C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc finger protein 281
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162702 ZNF281 9606 - 1:200404940-200410056 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294740 ZNF281-001 200404940-200410056 protein_coding
  ENST00000367352 ZNF281-003 200406730-200409992 protein_coding
  ENST00000367353 ZNF281-002 200406708-200410009 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000294740ENST00000367352ENST00000367353
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000294740 1.697±0.00 2.782±0.00 2.922±0.00 1.767±1.29 2.059±0.88 0.347±0.02 3.173±2.46 1.228±0.00 2.092±0.03 1.515±0.00 3.349±0.79 2.849±1.47 2.758±0.78
ENST00000367352 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.514±0.00 N/A N/A N/A
ENST00000367353 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.714±0.00 1.423±0.00 2.911±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MU CIL_0007MU_0001 UCNEbase 1:199778718-200463847

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001047 ISS core promoter binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0010172 ISS embryonic body morphogenesis
GO:0010629 IMP negative regulation of gene expression
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048863 ISS stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000567 ZNF281 (1 of 2) zinc finger protein 281 protein_coding Danio_rerio
ENSDARG00000035910 ZNF281 (2 of 2) zinc finger protein 281 protein_coding Danio_rerio
ENSMUSG00000041483 Zfp281 zinc finger protein 281 protein_coding Mus_musculus

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