C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transforming growth factor, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163235 TGFA 9606 - 2:70447280-70554193 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295400 TGFA-001 70447280-70554015 protein_coding
  ENST00000394241 TGFA-012 70456339-70553973 protein_coding
  ENST00000418333 TGFA-016 70450173-70553826 protein_coding
  ENST00000419940 TGFA-006 70449319-70465733 protein_coding
  ENST00000444975 TGFA-002 70450772-70553638 protein_coding
  ENST00000445399 TGFA-005 70449319-70553772 protein_coding
  ENST00000450929 TGFA-003 70450656-70553490 protein_coding
  ENST00000460808 TGFA-015 70456366-70553826 processed_transcript
  ENST00000474101 TGFA-010 70514859-70554193 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000295400ENST00000418333ENST00000419940
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000295400 0.099±0.00 1.399±0.00 1.367±0.00 4.999±0.00 0.144±0.07 0.146±0.08 0.070±0.00 0.213±0.02 0.103±0.00 1.371±0.61 0.326±0.01 0.152±0.00
ENST00000418333 N/A N/A N/A N/A N/A 0.070±0.00 N/A N/A N/A N/A N/A 1.304±0.80
ENST00000419940 N/A N/A N/A N/A 1.864±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001525 IEA angiogenesis
GO:0001948 IEA glycoprotein binding
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005886 NAS plasma membrane
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0008083 IDA growth factor activity
GO:0008283 TAS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0045741 IDA positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 IDA positive regulation of mitosis
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048523 IEA negative regulation of cellular process
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0051781 IEA positive regulation of cell division
GO:0060749 IEA mammary gland alveolus development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053939 tgfa transforming growth factor, alpha protein_coding Danio_rerio
ENSMUSG00000029999 Tgfa transforming growth factor alpha protein_coding Mus_musculus

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