C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plexin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164050 PLXNB1 9606 - 3:48403854-48430051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296440 PLXNB1-001 48403854-48430051 protein_coding
  ENST00000358536 PLXNB1-003 48403856-48429463 protein_coding
  ENST00000449094 PLXNB1-007 48413759-48424611 nonsense_mediated_decay
  ENST00000456774 PLXNB1-005 48404486-48424611 protein_coding
  ENST00000461261 PLXNB1-014 48411006-48412940 retained_intron
  ENST00000462738 PLXNB1-018 48418287-48419612 retained_intron
  ENST00000464294 PLXNB1-008 48414991-48416833 retained_intron
  ENST00000465117 PLXNB1-015 48413908-48415666 processed_transcript
  ENST00000466353 PLXNB1-019 48420079-48429481 processed_transcript
  ENST00000467913 PLXNB1-016 48413987-48415535 retained_intron
  ENST00000470525 PLXNB1-013 48410015-48411967 retained_intron
  ENST00000473683 PLXNB1-020 48422413-48423574 processed_transcript
  ENST00000473996 PLXNB1-006 48413220-48414980 retained_intron
  ENST00000478171 PLXNB1-011 48409399-48410365 retained_intron
  ENST00000483676 PLXNB1-012 48407022-48409719 retained_intron
  ENST00000483753 PLXNB1-009 48404509-48406065 retained_intron
  ENST00000484485 PLXNB1-017 48418189-48419744 processed_transcript
  ENST00000485535 PLXNB1-002 48403856-48414006 retained_intron
  ENST00000497627 PLXNB1-010 48406723-48409404 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296440ENST00000358536ENST00000456774ENST00000485535ENST00000497627
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296440 0.684±0.00 0.716±0.00 2.051±0.00 1.096±0.00 1.762±0.00 N/A N/A N/A 1.853±0.00 N/A 0.139±0.06 6.103±1.97 4.132±1.64 2.372±0.00
ENST00000358536 N/A 0.686±0.00 N/A 11.571±0.00 N/A N/A 4.478±0.00 N/A 3.429±0.00 3.384±0.00 0.202±0.00 4.497±0.28 1.960±0.04 N/A
ENST00000456774 N/A 0.619±0.00 N/A N/A N/A N/A 0.286±0.00 N/A N/A 0.516±0.00 0.110±0.00 N/A N/A N/A
ENST00000485535 2.032±0.00 1.175±0.00 5.075±0.00 5.725±4.04 3.366±0.68 4.355±1.83 N/A 7.763±3.06 2.479±0.80 2.827±2.02 0.535±0.00 6.745±3.52 N/A 2.420±0.58
ENST00000497627 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.141±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007U6 CIL_0007U6_0001 VISTA 3:47843366-48458182

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002116 IDA semaphorin receptor complex
GO:0004872 TAS:IEA receptor activity
GO:0004888 NAS transmembrane signaling receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005622 IEA intracellular
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0007162 IDA negative regulation of cell adhesion
GO:0007165 TAS:IEA signal transduction
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0008360 IDA regulation of cell shape
GO:0014068 ISS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0016477 NAS cell migration
GO:0017154 TAS semaphorin receptor activity
GO:0030215 TAS semaphorin receptor binding
GO:0032321 ISS positive regulation of Rho GTPase activity
GO:0032794 ISS GTPase activating protein binding
GO:0033689 ISS negative regulation of osteoblast proliferation
GO:0035556 NAS intracellular signal transduction
GO:0043931 ISS ossification involved in bone maturation
GO:0048812 ISS neuron projection morphogenesis
GO:0050772 IEA positive regulation of axonogenesis
GO:0051493 IDA regulation of cytoskeleton organization
GO:0071526 IDA semaphorin-plexin signaling pathway
GO:1900220 ISS semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017211 plxnb1b plexin b1b protein_coding Danio_rerio
ENSDARG00000075821 plxnb1a plexin b1a protein_coding Danio_rerio
ENSMUSG00000053646 Plxnb1 plexin B1 protein_coding Mus_musculus

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