C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164078 MST1R 9606 - 3:49887002-49903873 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296474 MST1R-001 49887002-49903637 protein_coding
  ENST00000344206 MST1R-002 49887165-49903609 protein_coding
  ENST00000411578 MST1R-007 49887005-49903866 nonsense_mediated_decay
  ENST00000434765 MST1R-011 49889950-49895816 protein_coding
  ENST00000440292 MST1R-010 49890547-49896073 protein_coding
  ENST00000463789 MST1R-013 49890570-49891942 retained_intron
  ENST00000467110 MST1R-009 49895431-49896138 retained_intron
  ENST00000468525 MST1R-006 49896120-49903609 retained_intron
  ENST00000485044 MST1R-005 49897987-49903609 retained_intron
  ENST00000490053 MST1R-012 49891771-49895439 retained_intron
  ENST00000493535 MST1R-004 49897987-49903609 retained_intron
  ENST00000497001 MST1R-003 49899006-49903609 retained_intron
  ENST00000612032 MST1R-201 49887007-49903609 protein_coding
  ENST00000613534 MST1R-202 49887007-49903609 protein_coding
  ENST00000621387 MST1R-203 49887007-49903873 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296474ENST00000344206ENST00000411578ENST00000434765ENST00000463789ENST00000468525ENST00000485044ENST00000490053ENST00000497001ENST00000612032ENST00000621387
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296474 N/A N/A N/A N/A N/A 0.438±0.00 N/A N/A N/A N/A N/A 0.331±0.00 0.213±0.08 N/A
ENST00000344206 N/A 0.198±0.00 N/A N/A N/A N/A 0.134±0.00 0.340±0.00 N/A 1.717±0.00 N/A 1.955±1.17 0.097±0.00 N/A
ENST00000411578 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.546±0.00 N/A 0.811±0.00
ENST00000434765 N/A 0.428±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.203±0.00 N/A N/A N/A
ENST00000463789 N/A N/A 0.826±0.00 N/A 2.785±0.00 N/A N/A N/A N/A 0.700±0.00 N/A N/A N/A N/A
ENST00000468525 N/A N/A N/A 0.034±0.00 N/A N/A N/A N/A 0.033±0.00 N/A N/A 0.671±0.00 0.126±0.01 N/A
ENST00000485044 N/A N/A N/A N/A N/A 1.436±0.00 0.204±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000490053 N/A N/A N/A 0.080±0.00 N/A N/A N/A N/A N/A 0.511±0.00 0.478±0.00 1.056±0.00 N/A N/A
ENST00000497001 N/A N/A 0.060±0.00 N/A N/A N/A N/A N/A 0.205±0.00 0.167±0.00 N/A N/A N/A N/A
ENST00000612032 N/A N/A N/A 0.041±0.00 N/A 1.778±0.00 0.328±0.00 0.420±0.00 0.192±0.00 1.059±0.00 N/A 2.328±0.00 0.321±0.04 1.012±0.00
ENST00000621387 0.219±0.00 N/A N/A N/A 0.501±0.00 N/A N/A N/A N/A N/A N/A 1.940±0.00 N/A 0.402±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004872 IEA receptor activity
GO:0005011 TAS macrophage colony-stimulating factor receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006928 TAS cellular component movement
GO:0006952 TAS defense response
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007338 TAS single fertilization
GO:0008284 TAS positive regulation of cell proliferation
GO:0009615 IDA response to virus
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019899 IPI enzyme binding
GO:0038145 TAS macrophage colony-stimulating factor signaling pathway
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0045087 IEA innate immune response
GO:0051897 IDA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004871 mst1rb macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b protein_coding Danio_rerio
ENSDARG00000060235 mst1ra macrophage stimulating 1 receptor (c-met-related tyrosine kinase), a protein_coding Danio_rerio
ENSMUSG00000032584 Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) protein_coding Mus_musculus

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