C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxyprostaglandin dehydrogenase 15-(NAD)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164120 HPGD 9606 - 4:174490177-174523154 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296521 HPGD-013 174491458-174522487 protein_coding
  ENST00000296522 HPGD-001 174490177-174522898 protein_coding
  ENST00000422112 HPGD-011 174491785-174522488 protein_coding
  ENST00000504433 HPGD-004 174506743-174522499 protein_coding
  ENST00000506910 HPGD-008 174493152-174523154 protein_coding
  ENST00000508330 HPGD-003 174491794-174522641 nonsense_mediated_decay
  ENST00000509512 HPGD-009 174491870-174493461 retained_intron
  ENST00000510835 HPGD-005 174491104-174522475 nonsense_mediated_decay
  ENST00000510901 HPGD-002 174491571-174523065 protein_coding
  ENST00000511499 HPGD-007 174491755-174495829 retained_intron
  ENST00000512410 HPGD-006 174495361-174522432 retained_intron
  ENST00000514584 HPGD-010 174493159-174522333 protein_coding
  ENST00000541923 HPGD-201 174490177-174522898 protein_coding
  ENST00000542498 HPGD-202 174490177-174522898 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296521ENST00000296522ENST00000504433ENST00000506910ENST00000508330ENST00000510835ENST00000512410ENST00000541923ENST00000542498
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296521 N/A N/A 0.076±0.00 N/A N/A N/A N/A N/A N/A N/A 0.648±0.00 23.784±0.00 N/A
ENST00000296522 1.353±0.00 N/A N/A 0.959±0.00 5.002±0.00 0.134±0.00 8.395±0.00 4.171±2.21 5.758±1.23 N/A 0.390±0.06 20.839±11.25 0.946±0.80
ENST00000504433 N/A N/A N/A 0.657±0.00 N/A N/A N/A N/A 3.657±0.00 N/A 0.327±0.00 22.935±11.49 N/A
ENST00000506910 N/A N/A 0.482±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.828±0.00
ENST00000508330 N/A N/A 0.174±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000510835 2.704±0.00 0.821±0.00 0.129±0.00 0.273±0.00 4.220±0.00 0.222±0.00 3.409±0.00 N/A N/A 0.502±0.00 0.736±0.08 21.230±10.70 0.836±0.00
ENST00000512410 N/A N/A N/A N/A N/A 0.246±0.00 N/A N/A N/A N/A 2.753±0.00 77.519±55.16 0.556±0.00
ENST00000541923 N/A N/A 0.137±0.00 0.340±0.00 3.606±0.00 0.142±0.00 1.342±0.00 N/A N/A N/A N/A N/A N/A
ENST00000542498 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.378±0.00 N/A 0.373±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00007U CIL_00007U_0002 CGP 4:174283677-174523154

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IDA:IEA catalytic activity
GO:0004957 IDA prostaglandin E receptor activity
GO:0005829 NAS cytosol
GO:0006693 IDA prostaglandin metabolic process
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007565 IDA female pregnancy
GO:0007567 IDA parturition
GO:0008152 IEA metabolic process
GO:0016323 IEA basolateral plasma membrane
GO:0016404 IDA 15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0016491 IEA oxidoreductase activity
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 TAS cyclooxygenase pathway
GO:0019372 TAS lipoxygenase pathway
GO:0030728 ISS ovulation
GO:0042803 TAS protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045786 IDA negative regulation of cell cycle
GO:0050662 IEA coenzyme binding
GO:0051287 IDA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070403 IDA NAD+ binding
GO:0070493 ISS thrombin receptor signaling pathway
GO:0097070 ISS ductus arteriosus closure
GO:2001300 TAS lipoxin metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012016 CU928070.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000031613 Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) protein_coding Mus_musculus

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