C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RPTOR independent companion of MTOR, complex 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164327 RICTOR 9606 - 5:38937919-39074408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296782 RICTOR-002 38940020-39074399 protein_coding
  ENST00000357387 RICTOR-001 38937919-39074408 protein_coding
  ENST00000503698 RICTOR-009 38954699-38959332 processed_transcript
  ENST00000505927 RICTOR-010 38942224-38943247 retained_intron
  ENST00000509567 RICTOR-007 38962951-38970620 processed_transcript
  ENST00000510711 RICTOR-005 38969687-39074389 retained_intron
  ENST00000511516 RICTOR-003 38940015-39074389 nonsense_mediated_decay
  ENST00000513566 RICTOR-004 38980880-39074399 retained_intron
  ENST00000514735 RICTOR-006 38981898-39074389 protein_coding
  ENST00000515846 RICTOR-008 38966815-38971961 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296782ENST00000357387
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296782 N/A N/A 1.654±0.00 N/A 2.598±0.00 2.660±0.00 1.936±0.00 N/A 3.924±0.00 7.535±0.00 2.669±0.00 4.147±0.00 N/A N/A
ENST00000357387 2.748±0.00 4.570±0.00 2.961±0.00 1.788±0.00 3.540±2.41 3.245±1.23 2.947±0.14 2.612±0.85 0.594±0.00 4.215±2.22 1.818±0.00 1.789±0.72 1.002±0.45 1.641±0.94

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009790 ISS embryo development
GO:0018105 IGI peptidyl-serine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031295 TAS T cell costimulation
GO:0031532 IMP actin cytoskeleton reorganization
GO:0031929 IEA TOR signaling
GO:0031932 IDA TORC2 complex
GO:0032008 IMP positive regulation of TOR signaling
GO:0032314 IEA regulation of Rac GTPase activity
GO:0032956 IMP regulation of actin cytoskeleton organization
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042325 IEA regulation of phosphorylation
GO:0043022 IEA ribosome binding
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051896 IDA regulation of protein kinase B signaling
GO:0051897 IEA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002020 rictorb rapamycin-insensitive companion of mTOR b protein_coding Danio_rerio
ENSDARG00000059414 rictora rapamycin-insensitive companion of mTOR a protein_coding Danio_rerio
ENSDARG00000059418 RICTOR (3 of 3) RPTOR independent companion of MTOR, complex 2 protein_coding Danio_rerio
ENSMUSG00000050310 Rictor RPTOR independent companion of MTOR, complex 2 protein_coding Mus_musculus

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