C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kallikrein B, plasma (Fletcher factor) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164344 KLKB1 9606 + 4:186208979-186258471 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264690 KLKB1-001 186227402-186258471 protein_coding
  ENST00000414291 KLKB1-003 186227518-186236887 protein_coding
  ENST00000428196 KLKB1-002 186226438-186236896 protein_coding
  ENST00000446598 KLKB1-004 186227507-186238304 protein_coding
  ENST00000467271 KLKB1-005 186251032-186252163 retained_intron
  ENST00000511406 KLKB1-006 186227559-186258292 retained_intron
  ENST00000511608 KLKB1-008 186208979-186258469 protein_coding
  ENST00000513864 KLKB1-007 186227518-186258470 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverENST00000264690ENST00000511608
Transcript ID Kidney Liver
ENST00000264690 19.802±0.00 N/A
ENST00000511608 20.039±0.00 24.640±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006W0 CIL_0006W0_0002 CGP 4:186104419-186213456

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002542 TAS Factor XII activation
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA:NAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007596 IEA:TAS blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0031638 TAS zymogen activation
GO:0031639 IDA plasminogen activation
GO:0042730 IEA fibrinolysis
GO:0051919 IDA positive regulation of fibrinolysis
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000031640 Klkb1 kallikrein B, plasma 1 protein_coding Mus_musculus

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