C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164924 YWHAZ 9606 - 8:100916525-100953388 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000353245 YWHAZ-002 100918686-100953341 protein_coding
  ENST00000395948 YWHAZ-008 100920603-100952990 protein_coding
  ENST00000395951 YWHAZ-011 100920630-100950557 protein_coding
  ENST00000395953 YWHAZ-009 100920587-100951594 protein_coding
  ENST00000395956 YWHAZ-004 100918683-100951449 protein_coding
  ENST00000395957 YWHAZ-001 100916525-100952983 protein_coding
  ENST00000395958 YWHAZ-201 100918577-100952129 protein_coding
  ENST00000418997 YWHAZ-007 100948596-100952619 protein_coding
  ENST00000419477 YWHAZ-010 100920642-100951276 protein_coding
  ENST00000437293 YWHAZ-006 100948614-100952883 protein_coding
  ENST00000457309 YWHAZ-202 100918579-100952993 protein_coding
  ENST00000480304 YWHAZ-003 100922438-100951969 retained_intron
  ENST00000492736 YWHAZ-005 100951956-100953388 processed_transcript
  ENST00000517727 YWHAZ-016 100923987-100950540 retained_intron
  ENST00000518736 YWHAZ-015 100923985-100951595 retained_intron
  ENST00000521309 YWHAZ-012 100919829-100952019 protein_coding
  ENST00000521328 YWHAZ-018 100924922-100950996 protein_coding
  ENST00000521607 YWHAZ-017 100920716-100948900 protein_coding
  ENST00000522542 YWHAZ-013 100919829-100948162 protein_coding
  ENST00000522819 YWHAZ-022 100920526-100935055 protein_coding
  ENST00000523131 YWHAZ-020 100948663-100952604 protein_coding
  ENST00000523848 YWHAZ-019 100919062-100924988 nonsense_mediated_decay
  ENST00000523938 YWHAZ-021 100948735-100952552 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000353245ENST00000395956ENST00000395958ENST00000419477ENST00000457309ENST00000521309ENST00000521328ENST00000522542ENST00000523848
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000353245 N/A N/A 7.542±0.00 44.776±0.00 17.493±0.00 18.833±0.00 N/A 3.894±0.00 N/A 29.901±0.00 2.641±0.00 60.118±26.98 26.917±0.00 23.214±0.00
ENST00000395956 20.603±0.00 20.190±0.00 N/A 95.040±0.00 45.095±0.00 33.452±0.00 17.408±0.00 29.127±0.00 N/A 54.701±0.00 10.070±0.00 N/A N/A 37.027±0.00
ENST00000395958 37.080±0.00 34.384±0.00 N/A 34.374±19.55 35.964±0.00 20.430±7.61 8.239±0.00 21.530±0.00 10.265±0.00 30.422±0.00 4.913±3.71 60.928±38.54 79.198±20.35 26.017±0.00
ENST00000419477 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.981±0.00 N/A N/A N/A
ENST00000457309 N/A N/A 4.071±0.00 19.983±0.00 20.164±0.00 17.073±0.00 7.216±0.00 10.302±0.00 33.688±0.00 12.485±0.00 N/A 41.968±20.51 N/A N/A
ENST00000521309 N/A N/A 9.161±0.00 83.250±0.00 44.264±0.00 28.737±0.00 14.570±1.75 N/A 46.880±0.00 N/A 5.899±0.00 145.306±48.96 128.262±0.00 61.410±27.37
ENST00000521328 N/A N/A 22.329±0.00 N/A 76.413±0.00 N/A N/A N/A N/A N/A N/A 118.562±0.00 N/A N/A
ENST00000522542 N/A N/A N/A 65.315±0.00 74.972±0.00 23.390±0.00 N/A 7.965±0.00 N/A 36.433±0.00 N/A N/A N/A N/A
ENST00000523848 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 281.288±0.00 121.760±0.00 146.395±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002553 IEA histamine secretion by mast cell
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006605 IEA protein targeting
GO:0006626 IEA protein targeting to mitochondrion
GO:0006915 TAS apoptotic process
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0010467 TAS gene expression
GO:0010941 IEA regulation of cell death
GO:0014069 IEA postsynaptic density
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0019901 IPI protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030168 TAS platelet activation
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031252 IEA cell leading edge
GO:0032403 IEA protein complex binding
GO:0042493 IEA response to drug
GO:0042629 IEA mast cell granule
GO:0042802 IPI identical protein binding
GO:0043066 TAS negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000022285 Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide protein_coding Mus_musculus

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