C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome b-245, beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165168 CYBB 9606 + X:37780011-37813461 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378588 CYBB-001 37780011-37813461 protein_coding
  ENST00000492288 CYBB-002 37798220-37804079 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378588
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378588 7.875±0.00 7.785±0.00 1.810±0.00 1.757±0.28 7.984±2.24 2.682±2.30 2.859±1.11 3.609±0.96 5.102±3.11 17.219±12.92 0.382±0.00 2.967±1.92 15.656±1.21 0.662±0.60

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005244 IEA voltage-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005791 IEA rough endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006801 IDA superoxide metabolic process
GO:0006811 IEA ion transport
GO:0006954 ISS inflammatory response
GO:0007584 IEA response to nutrient
GO:0009055 IDA electron carrier activity
GO:0016175 TAS superoxide-generating NADPH oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0020037 IMP heme binding
GO:0030425 IEA dendrite
GO:0030670 TAS phagocytic vesicle membrane
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042493 IEA response to drug
GO:0042554 IDA superoxide anion generation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043020 TAS NADPH oxidase complex
GO:0043025 IEA neuronal cell body
GO:0045087 TAS innate immune response
GO:0045730 TAS respiratory burst
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0050660 IMP flavin adenine dinucleotide binding
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0051701 TAS interaction with host
GO:0055114 IDA:IEA oxidation-reduction process
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056615 cybb cytochrome b-245, beta polypeptide (chronic granulomatous disease) protein_coding Danio_rerio
ENSMUSG00000015340 Cybb cytochrome b-245, beta polypeptide protein_coding Mus_musculus

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