C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member E2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165568 AKR1E2 9606 + 10:4786629-4848062 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298375 AKR1E2-006 4826254-4848062 protein_coding
  ENST00000334019 AKR1E2-014 4826296-4847745 protein_coding
  ENST00000345253 AKR1E2-010 4826296-4847745 protein_coding
  ENST00000441590 AKR1E2-001 4833355-4845811 processed_transcript
  ENST00000462718 AKR1E2-003 4786709-4839819 processed_transcript
  ENST00000463345 AKR1E2-002 4826234-4848062 nonsense_mediated_decay
  ENST00000474119 AKR1E2-004 4826177-4848062 nonsense_mediated_decay
  ENST00000487985 AKR1E2-005 4839784-4847345 protein_coding
  ENST00000525281 AKR1E2-008 4826255-4846199 processed_transcript
  ENST00000525572 AKR1E2-012 4833400-4841857 nonsense_mediated_decay
  ENST00000525627 AKR1E2-011 4826286-4837566 processed_transcript
  ENST00000532248 AKR1E2-009 4826296-4847296 protein_coding
  ENST00000533295 AKR1E2-007 4786629-4837583 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298375ENST00000334019ENST00000345253ENST00000462718ENST00000463345ENST00000474119ENST00000525281ENST00000525572ENST00000525627ENST00000532248ENST00000533295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298375 0.177±0.00 0.448±0.00 N/A N/A 0.424±0.00 N/A N/A 0.231±0.00 N/A 0.450±0.00 N/A 0.205±0.06 0.086±0.00 6.638±0.00
ENST00000334019 N/A N/A N/A 1.368±0.00 N/A N/A N/A 0.097±0.00 0.658±0.59 0.156±0.00 N/A N/A 0.319±0.08 3.949±0.00
ENST00000345253 0.304±0.00 N/A N/A 0.535±0.00 0.528±0.00 0.582±0.00 N/A N/A N/A 0.464±0.18 N/A 0.721±0.00 N/A N/A
ENST00000462718 N/A N/A N/A N/A 1.536±0.00 0.375±0.18 0.425±0.00 N/A 1.054±0.00 1.874±0.00 0.349±0.00 2.142±0.00 0.744±0.00 5.921±0.00
ENST00000463345 0.163±0.00 0.400±0.00 N/A N/A 0.482±0.00 N/A 0.338±0.00 N/A 0.332±0.00 N/A N/A 0.093±0.00 0.116±0.00 5.185±1.79
ENST00000474119 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.408±0.00 N/A N/A
ENST00000525281 N/A N/A N/A N/A 0.477±0.00 N/A 0.129±0.00 N/A N/A N/A N/A 0.627±0.41 0.233±0.00 5.917±0.00
ENST00000525572 N/A N/A N/A N/A N/A N/A N/A 0.377±0.00 0.152±0.00 0.374±0.00 1.002±0.00 2.454±0.00 0.449±0.24 N/A
ENST00000525627 N/A N/A N/A N/A N/A N/A 0.375±0.00 N/A N/A 0.626±0.00 N/A N/A N/A N/A
ENST00000532248 N/A N/A 0.584±0.00 1.458±0.00 1.299±0.00 N/A 1.136±0.00 0.456±0.00 1.241±0.00 1.218±0.00 N/A 2.652±0.00 0.147±0.00 6.086±0.00
ENST00000533295 N/A N/A N/A 0.238±0.00 N/A N/A N/A N/A N/A N/A N/A 0.125±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0016491 IEA oxidoreductase activity
GO:0050571 IEA 1,5-anhydro-D-fructose reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045598 si:dkey-180p18.9 aldo-keto reductase family 1, member B1 (aldose reductase) protein_coding Danio_rerio
ENSMUSG00000045410 Akr1e1 aldo-keto reductase family 1, member E1 protein_coding Mus_musculus

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