C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipase, hepatic
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166035 LIPC 9606 + 15:58410569-58569843 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299022 LIPC-001 58431798-58569843 protein_coding
  ENST00000356113 LIPC-002 58410569-58568873 protein_coding
  ENST00000414170 LIPC-003 58410572-58566471 protein_coding
  ENST00000433326 LIPC-005 58431991-58568952 protein_coding
  ENST00000559845 LIPC-004 58431991-58564008 retained_intron
  ENST00000560257 LIPC-006 58410581-58432363 retained_intron
  ENST00000560664 LIPC-007 58541748-58548572 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299022ENST00000356113ENST00000414170ENST00000433326ENST00000559845ENST00000560257ENST00000560664
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299022 N/A N/A N/A N/A N/A N/A N/A 7.737±0.00 3.183±0.00 N/A N/A 0.030±0.00 0.026±0.00 0.024±0.00
ENST00000356113 0.065±0.00 0.362±0.00 0.193±0.00 0.314±0.00 N/A 0.069±0.00 0.078±0.00 3.155±2.63 0.135±0.00 0.080±0.00 N/A 0.148±0.01 0.242±0.00 0.059±0.03
ENST00000414170 0.024±0.00 N/A N/A 0.030±0.00 0.048±0.01 N/A N/A 0.355±0.00 N/A N/A N/A 0.017±0.00 N/A N/A
ENST00000433326 N/A N/A 0.587±0.00 N/A N/A 0.132±0.05 N/A 4.037±2.00 35.272±0.00 N/A N/A 0.159±0.10 0.292±0.07 N/A
ENST00000559845 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.063±0.00 0.363±0.00 0.029±0.00
ENST00000560257 N/A N/A N/A N/A 0.311±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.147±0.02
ENST00000560664 0.126±0.00 N/A 1.154±0.00 0.715±0.00 0.553±0.00 N/A 0.293±0.00 4.187±0.00 27.697±0.00 0.344±0.00 0.599±0.00 0.469±0.00 0.115±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000501 CIL_000501_0002 CGP 15:57953424-58497866
CIL_0008MN CIL_0008MN_0001 VISTA 15:58226062-58826684

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004620 TAS phospholipase activity
GO:0004806 IDA triglyceride lipase activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005615 IDA extracellular space
GO:0006629 IEA lipid metabolic process
GO:0006633 IDA fatty acid biosynthetic process
GO:0008201 IEA heparin binding
GO:0008203 IEA cholesterol metabolic process
GO:0016298 IEA lipase activity
GO:0019433 IDA triglyceride catabolic process
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 IEA cholesterol transport
GO:0034185 ISS apolipoprotein binding
GO:0034364 IEA high-density lipoprotein particle
GO:0034372 IDA very-low-density lipoprotein particle remodeling
GO:0034373 TAS intermediate-density lipoprotein particle remodeling
GO:0034374 IMP low-density lipoprotein particle remodeling
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034382 TAS chylomicron remnant clearance
GO:0034638 TAS phosphatidylcholine catabolic process
GO:0042632 IMP cholesterol homeostasis
GO:0043691 IC reverse cholesterol transport
GO:0052689 IEA carboxylic ester hydrolase activity
GO:0070328 IMP triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053476 lipca lipase, hepatic a protein_coding Danio_rerio
ENSDARG00000090486 LIPC (2 of 2) lipase, hepatic protein_coding Danio_rerio
ENSMUSG00000032207 Lipc lipase, hepatic protein_coding Mus_musculus

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